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Nature Medicine|June 13, 2018
A transcriptionally and functionally distinct PD-1+ CD8+ T cell pool with predictive potential in non-small-cell lung cancer treated with PD-1 blockadeDaniela S Thommen, Viktor H Koelzer, Petra Herzig, et al.Nature Immunology|October 30, 2025
Cancer suppresses mitochondrial chaperone activity in macrophages to drive immune evasionHaoxin Zhao, Jaeoh Park, Yuzhu Wang, et al.Biorxiv : the Preprint Server for Biology|June 4, 2026
Mitochondrial copper stabilizes lipoylated TCA cycle proteins to sustain metabolism and proliferationSantanu Ghosh, Andrew F Jarvis, Jordi C J Hintzen, et al.Nature Immunology|May 25, 2021
Metabolic reprogramming of terminally exhausted CD8+ T cells by IL-10 enhances anti-tumor immunityYugang Guo, Yu-Qing Xie, Min Gao, et al.Nature Immunology|October 6, 2020
Disturbed mitochondrial dynamics in CD8+ TILs reinforce T cell exhaustionYi-Ru Yu, Hana Imrichova, Haiping Wang, et al.Cell Reports|November 17, 2022
CD8+ T cell metabolic rewiring defined by scRNA-seq identifies a critical role of ASNS expression dynamics in T cell differentiationJuan Fernández-García, Fabien Franco, Sweta Parik, et al.Nature Immunology|October 23, 2021
Tumor-induced reshuffling of lipid composition on the endoplasmic reticulum membrane sustains macrophage survival and pro-tumorigenic activityGiusy Di Conza, Chin-Hsien Tsai, Hector Gallart-Ayala, et al.Nature Immunology|February 19, 2020
CD36-mediated metabolic adaptation supports regulatory T cell survival and function in tumorsHaiping Wang, Fabien Franco, Yao-Chen Tsui, et al.Cell|September 1, 2015
Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell ResponsesPing-Chih Ho, Jessica Dauz Bihuniak, Andrew N Macintyre, et al.The Journal of Clinical Investigation|March 12, 2026
Inhibiting LSD1 unlocks retinoid AP-1 programming to activate epithelial immunity and skin tumor suppressionNina Kuprasertkul, Alyssa F Moore, Carina A D'souza, et al.Pageof 13