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Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|March 28, 2013
Inhibition of NF-κB-mediated signaling by the cyclin-dependent kinase inhibitor CR8 overcomes prosurvival stimuli to induce apoptosis in chronic lymphocytic leukemia cellsEmilio Cosimo, Alison M McCaig, Luke J M Carter-Brzezinski, et al.Science Translational Medicine|September 29, 2021
ULK1 inhibition promotes oxidative stress-induced differentiation and sensitizes leukemic stem cells to targeted therapyAngela Ianniciello, Martha M Zarou, Kevin M Rattigan, et al.Nature Communications|January 21, 2024
Activating p53 abolishes self-renewal of quiescent leukaemic stem cells in residual CML diseaseMary T Scott, Wei Liu, Rebecca Mitchell, et al.Cell Death Discovery|April 25, 2025
The chemical chaperone 4-phenylbutyric acid rescues molecular cell defects of COL3A1 mutations that cause vascular Ehlers Danlos SyndromeRamla Omar, Michelle Aw Lee, Laura Gonzalez-Trueba, et al.Blood|January 12, 2013
Megakaryocytes assemble podosomes that degrade matrix and protrude through basement membraneHannah Schachtner, Simon D J Calaminus, Amy Sinclair, et al.Cancers|December 11, 2022
PKCβ Facilitates Leukemogenesis in Chronic Lymphocytic Leukaemia by Promoting Constitutive BCR-Mediated SignallingJodie Hay, Anuradha Tarafdar, Ailsa K Holroyd, et al.Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|December 19, 2018
AKT/mTORC2 Inhibition Activates FOXO1 Function in CLL Cells Reducing B-Cell Receptor-Mediated SurvivalEmilio Cosimo, Anuradha Tarafdar, Michael W Moles, et al.Blood|May 26, 2016
CXCR2 and CXCL4 regulate survival and self-renewal of hematopoietic stem/progenitor cellsAmy Sinclair, Laura Park, Mansi Shah, et al.Nature Communications|August 17, 2023
Pyruvate anaplerosis is a targetable vulnerability in persistent leukaemic stem cellsKevin M Rattigan, Zuzana Brabcova, Daniele Sarnello, et al.Leukemia|September 7, 2018
Targeting quiescent leukemic stem cells using second generation autophagy inhibitorsPablo Baquero, Amy Dawson, Arunima Mukhopadhyay, et al.Pageof 5