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Viruses|November 27, 2025
The First CRISPR-Based Therapeutic (SL_1.52) for African Swine Fever Is Effective in SwineNaveen Verma, Alison O'Mahony, Roky Mohammad, et al.
Plos One|March 19, 2013
Regulation of IL-17A production is distinct from IL-17F in a primary human cell co-culture model of T cell-mediated B cell activationAndrew C Melton, Jennifer Melrose, Liisa Alajoki, et al.
Nature Chemical Biology|March 4, 2014
Dual kinase-bromodomain inhibitors for rationally designed polypharmacologyPietro Ciceri, Susanne Müller, Alison O'Mahony, et al.
Proceedings of the National Academy of Sciences of the United States of America|August 12, 2015
CBP30, a selective CBP/p300 bromodomain inhibitor, suppresses human Th17 responsesAriane Hammitzsch, Cynthia Tallant, Oleg Fedorov, et al.
The Journal of Pharmacology and Experimental Therapeutics|January 10, 2012
RN486, a selective Bruton's tyrosine kinase inhibitor, abrogates immune hypersensitivity responses and arthritis in rodentsDaigen Xu, Yong Kim, Jennifer Postelnek, et al.
Proceedings of the National Academy of Sciences of the United States of America|February 1, 2018
Targeting JAK2 reduces GVHD and xenograft rejection through regulation of T cell differentiationBrian C Betts, David Bastian, Supinya Iamsawat, et al.
Nature Chemical Biology|May 1, 2012
A selective inhibitor reveals PI3Kγ dependence of T(H)17 cell differentiationGiovanna Bergamini, Kathryn Bell, Satoko Shimamura, et al.
Iscience|August 22, 2022
A tubulin binding molecule drives differentiation of acute myeloid leukemia cellsThomas R Jackson, Aini Vuorinen, Laia Josa-Culleré, et al.
Journal of Medicinal Chemistry|April 27, 2016
Identification of a Chemical Probe for Family VIII Bromodomains through Optimization of a Fragment HitBrian S Gerstenberger, John D Trzupek, Cynthia Tallant, et al.
Cancer Research|November 11, 2015
Generation of a Selective Small Molecule Inhibitor of the CBP/p300 Bromodomain for Leukemia TherapySarah Picaud, Oleg Fedorov, Angeliki Thanasopoulou, et al.
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