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International Immunopharmacology|September 3, 2024
Pharmacological and biochemical insights into lead-induced hepatotoxicity: Pathway interplay and the protective effects of arbutin via the oral and intraperitoneal routes in silico and in vivoAlzahraa Ahmed Elhemiely, Alshaymaa DarwishEuropean Journal of Pharmacology|August 20, 2023
Canagliflozin alleviates experimentally induced benign prostate hyperplasia in a rat model: exploring potential mechanisms involving mir-128b/EGFR/EGF and JAK2/STAT3 signaling pathways through in silico and in vivo investigationsEman M Elbaz, Alshaymaa Darwish, Amany M Gad, et al.International Journal of Biological Macromolecules|January 29, 2026
Exploring the cardioprotective potential of Hyphaene Thebaica L. extract, Bacillus-derived proteases, and vitamin E against doxorubicin-induced cardiotoxicity: Insights into mechanisms and Wnt/β-catenin/GSK3β signaling modulationShaimaa M Azzam, Gad Elsayed Mohamed Salem, Amina A S Abdel Rahman, et al.International Journal of Biological Macromolecules|April 4, 2024
Therapeutic potential of proteases in acute lung injury and respiratory distress syndrome via TLR4/Nrf2/NF-kB signaling modulationHend Mohamed Anwar, Gad Elsayed Mohamed Salem, Hanan M Abd El-Latief, et al.Current Drug Targets|June 2, 2026
Microbial Proteases: Pioneering Tools for Modern Therapeutic InnovationsGad Elsayed Mohamed Salem, Mohamed A El-Sakhawy, Alshaymaa Darwish, et al.Life Sciences|November 7, 2023
In silico and in vivo analysis of the relationship between ADHD and social isolation in pups rat model: Implication of redox mechanisms, and the neuroprotective impact of PunicalaginKarema Abu-Elfotuh, Alshaymaa Darwish, Heba M A Elsanhory, et al.Journal of Ethnopharmacology|January 13, 2024
A mechanistic exploration of the metabolome of African mango seeds and its potential to alleviate cognitive impairment induced by high-fat/high-carbohydrate diets: Involvement of PI3K/AKT/GSK-3β/CREB, PERK/CHOP/Bcl-2, and AMPK/SIRT-1/mTOR AxesYassmin Raafat Hassan, Riham A El-Shiekh, Hala M El Hefnawy, et al.Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie|August 4, 2023
Revealing how phenytoin triggers liver damage and the potential protective effects of Balanites Aegyptiaca fruit extracts: Exploring Nrf2/MAPK/ Beclin-1 signaling pathwaysShaimaa M Azzam, Marwa Refaat Abdel Khalek, Amina A S Abdel Rahman, et al.Pharmaceutics|October 28, 2023
Punicalagin's Protective Effects on Parkinson's Progression in Socially Isolated and Socialized Rats: Insights into Multifaceted PathwayHoda A Salem, Karema Abu-Elfotuh, Sharifa Alzahrani, et al.Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie|March 30, 2025
Combining vinpocetine or cocoa with levodopa, Coenzyme Q10 and vitamin B complex mitigates rotenone-induced Parkinson's disease in rats: Impact on Nrf2/HO-1, NF-kB, AMPK/SIRT-1/Beclin-1, AKT/GSK-3β/CREB/BDNF and Apoptotic PathwaysKarema Abu-Elfotuh, Mohammed D Al-Rekabi, Ashwaq N Abbas, et al.Pageof 2