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Proceedings of the National Academy of Sciences of the United States of America|July 22, 2015
Small-molecule enhancers of autophagy modulate cellular disease phenotypes suggested by human geneticsSzu-Yu Kuo, Adam B Castoreno, Leslie N Aldrich, et al.Proceedings of the National Academy of Sciences of the United States of America|March 22, 2012
Chromatin-targeting small molecules cause class-specific transcriptional changes in pancreatic endocrine cellsStefan Kubicek, Joshua C Gilbert, Dina Fomina-Yadlin, et al.Molecular and Cellular Biology|June 14, 2021
The Cyclin-Dependent Kinase 8 (CDK8) Inhibitor DCA Promotes a Tolerogenic Chemical Immunophenotype in CD4+ T Cells via a Novel CDK8-GATA3-FOXP3 PathwayAzlann Arnett, Keagan G Moo, Kaitlin J Flynn, et al.Cell|January 21, 2014
Regulation of ferroptotic cancer cell death by GPX4Wan Seok Yang, Rohitha SriRamaratnam, Matthew E Welsch, et al.ACS Chemical Biology|May 26, 2016
Development of Chemical Probes for Investigation of Salt-Inducible Kinase Function in VivoThomas B Sundberg, Yanke Liang, Huixian Wu, et al.Proceedings of the National Academy of Sciences of the United States of America|October 27, 2017
Small-molecule inhibitors directly target CARD9 and mimic its protective variant in inflammatory bowel diseaseElizaveta S Leshchiner, Jason S Rush, Michael A Durney, et al.Proceedings of the National Academy of Sciences of the United States of America|August 13, 2014
Small-molecule screening identifies inhibition of salt-inducible kinases as a therapeutic strategy to enhance immunoregulatory functions of dendritic cellsThomas B Sundberg, Hwan Geun Choi, Joo-Hye Song, et al.Cancer Discovery|December 16, 2014
Linking tumor mutations to drug responses via a quantitative chemical-genetic interaction mapMaria M Martins, Alicia Y Zhou, Alexandra Corella, et al.Immunity|October 22, 2015
Ubiquitin Ligase TRIM62 Regulates CARD9-Mediated Anti-fungal Immunity and Intestinal InflammationZhifang Cao, Kara L Conway, Robert J Heath, et al.Nature Chemical Biology|August 15, 2017
Small-molecule studies identify CDK8 as a regulator of IL-10 in myeloid cellsLiv Johannessen, Thomas B Sundberg, Daniel J O'Connell, et al.Pageof 5