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Gigascience|March 23, 2017
A dataset of images and morphological profiles of 30 000 small-molecule treatments using the Cell Painting assayMark-Anthony Bray, Sigrun M Gustafsdottir, Mohammad H Rohban, et al.Nature Chemical Biology|December 15, 2015
Identification of cancer-cytotoxic modulators of PDE3A by predictive chemogenomicsLuc de Waal, Timothy A Lewis, Matthew G Rees, et al.Nature Biotechnology|March 2, 2016
High-throughput identification of genotype-specific cancer vulnerabilities in mixtures of barcoded tumor cell linesChanning Yu, Aristotle M Mannan, Griselda Metta Yvone, et al.Elife|May 23, 2015
The kinase DYRK1A reciprocally regulates the differentiation of Th17 and regulatory T cellsBernard Khor, John D Gagnon, Gautam Goel, et al.Gastroenterology|August 27, 2013
Atg16l1 is required for autophagy in intestinal epithelial cells and protection of mice from Salmonella infectionKara L Conway, Petric Kuballa, Joo-Hye Song, et al.Proceedings of the National Academy of Sciences of the United States of America|May 14, 2014
Atg16L1 T300A variant decreases selective autophagy resulting in altered cytokine signaling and decreased antibacterial defenseKara G Lassen, Petric Kuballa, Kara L Conway, et al.Proceedings of the National Academy of Sciences of the United States of America|July 16, 2014
Toward performance-diverse small-molecule libraries for cell-based phenotypic screening using multiplexed high-dimensional profilingMathias J Wawer, Kejie Li, Sigrun M Gustafsdottir, et al.Cancer Discovery|October 21, 2015
Harnessing Connectivity in a Large-Scale Small-Molecule Sensitivity DatasetBrinton Seashore-Ludlow, Matthew G Rees, Jaime H Cheah, et al.Nature Chemical Biology|December 15, 2015
Correlating chemical sensitivity and basal gene expression reveals mechanism of actionMatthew G Rees, Brinton Seashore-Ludlow, Jaime H Cheah, et al.Cell|September 3, 2013
An interactive resource to identify cancer genetic and lineage dependencies targeted by small moleculesAmrita Basu, Nicole E Bodycombe, Jaime H Cheah, et al.Pageof 5