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Amanda Mathis

Showing results (11-20 of 20) with videos related to

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Journal of Medicinal Chemistry|November 15, 2013
Imidazopyridazine hepatitis C virus polymerase inhibitors. Structure-activity relationship studies and the discovery of a novel, traceless prodrug mechanismMartin Leivers, John F Miller, Stephanie A Chan, et al.
Clinical Pharmacology in Drug Development|April 30, 2016
A randomized, double blind, dose escalation, first time in human study to assess the safety, tolerability, pharmacokinetics, and antiviral activity of single doses of GSK2485852 in chronically infected hepatitis C subjectsDavid A Wilfret, Jill Walker, Christian Voitenleitner, et al.
Journal of Medicinal Chemistry|August 16, 2013
Discovery of selective small molecule type III phosphatidylinositol 4-kinase alpha (PI4KIIIα) inhibitors as anti hepatitis C (HCV) agentsAnna L Leivers, Matthew Tallant, J Brad Shotwell, et al.
Antimicrobial Agents and Chemotherapy|August 12, 2015
Preclinical Characterization and In Vivo Efficacy of GSK8853, a Small-Molecule Inhibitor of the Hepatitis C Virus NS4B ProteinJeffrey J Pouliot, Michael Thomson, Mi Xie, et al.
Journal of Medicinal Chemistry|February 15, 2019
Design of N-Benzoxaborole Benzofuran GSK8175-Optimization of Human Pharmacokinetics Inspired by Metabolites of a Failed Clinical HCV InhibitorPek Y Chong, J Brad Shotwell, John Miller, et al.
Science Translational Medicine|June 12, 2020
A direct-acting antiviral drug abrogates viremia in Zika virus-infected rhesus macaquesSo-Yon Lim, Christa E Osuna, Katharine Best, et al.
British Journal of Pharmacology|October 21, 2020
A novel class of fast-acting antimalarial agents: Substituted 15-membered azalidesMihaela Peric, Dijana Pešić, Sulejman Alihodžić, et al.
ACS Medicinal Chemistry Letters|June 6, 2014
Imidazo[1,2-a]pyridines That Directly Interact with Hepatitis C NS4B: Initial Preclinical CharacterizationJ Brad Shotwell, Subramanian Baskaran, Pek Chong, et al.
Journal of Medicinal Chemistry|April 3, 2013
Hepatitis C replication inhibitors that target the viral NS4B proteinJohn F Miller, Pek Y Chong, J Brad Shotwell, et al.
Journal of Medicinal Chemistry|May 16, 2013
Discovery of a potent boronic acid derived inhibitor of the HCV RNA-dependent RNA polymeraseAndrew Maynard, Renae M Crosby, Byron Ellis, et al.
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Showing results (11-20 of 20) with videos related to

Sort By:
Pageof 2
You have reached the last page of results.This site can display upto 20 results.
Journal of Medicinal Chemistry|November 15, 2013
Imidazopyridazine hepatitis C virus polymerase inhibitors. Structure-activity relationship studies and the discovery of a novel, traceless prodrug mechanismMartin Leivers, John F Miller, Stephanie A Chan, et al.
Clinical Pharmacology in Drug Development|April 30, 2016
A randomized, double blind, dose escalation, first time in human study to assess the safety, tolerability, pharmacokinetics, and antiviral activity of single doses of GSK2485852 in chronically infected hepatitis C subjectsDavid A Wilfret, Jill Walker, Christian Voitenleitner, et al.
Journal of Medicinal Chemistry|August 16, 2013
Discovery of selective small molecule type III phosphatidylinositol 4-kinase alpha (PI4KIIIα) inhibitors as anti hepatitis C (HCV) agentsAnna L Leivers, Matthew Tallant, J Brad Shotwell, et al.
Antimicrobial Agents and Chemotherapy|August 12, 2015
Preclinical Characterization and In Vivo Efficacy of GSK8853, a Small-Molecule Inhibitor of the Hepatitis C Virus NS4B ProteinJeffrey J Pouliot, Michael Thomson, Mi Xie, et al.
Journal of Medicinal Chemistry|February 15, 2019
Design of N-Benzoxaborole Benzofuran GSK8175-Optimization of Human Pharmacokinetics Inspired by Metabolites of a Failed Clinical HCV InhibitorPek Y Chong, J Brad Shotwell, John Miller, et al.
Science Translational Medicine|June 12, 2020
A direct-acting antiviral drug abrogates viremia in Zika virus-infected rhesus macaquesSo-Yon Lim, Christa E Osuna, Katharine Best, et al.
British Journal of Pharmacology|October 21, 2020
A novel class of fast-acting antimalarial agents: Substituted 15-membered azalidesMihaela Peric, Dijana Pešić, Sulejman Alihodžić, et al.
ACS Medicinal Chemistry Letters|June 6, 2014
Imidazo[1,2-a]pyridines That Directly Interact with Hepatitis C NS4B: Initial Preclinical CharacterizationJ Brad Shotwell, Subramanian Baskaran, Pek Chong, et al.
Journal of Medicinal Chemistry|April 3, 2013
Hepatitis C replication inhibitors that target the viral NS4B proteinJohn F Miller, Pek Y Chong, J Brad Shotwell, et al.
Journal of Medicinal Chemistry|May 16, 2013
Discovery of a potent boronic acid derived inhibitor of the HCV RNA-dependent RNA polymeraseAndrew Maynard, Renae M Crosby, Byron Ellis, et al.
Pageof 2