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The Journal of Biological Chemistry|December 1, 2006
Monoclonal antibody clearance. Impact of modulating the interaction of IgG with the neonatal Fc receptorAmita Datta-Mannan, Derrick R Witcher, Ying Tang, et al.
The Journal of Pharmacology and Experimental Therapeutics|December 20, 2012
An engineered human follistatin variant: insights into the pharmacokinetic and pharmocodynamic relationships of a novel molecule with broad therapeutic potentialAmita Datta-Mannan, Benjamin Yaden, Venkatesh Krishnan, et al.
Clinical Pharmacology and Therapeutics|June 12, 2024
Identification of a Safe and Tolerable Carbamazepine Dosing Paradigm that Facilitates Effective Evaluation of CYP3A4 InductionAmita Datta-Mannan, Elaine Shanks, Eunice Yuen, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|September 11, 2015
Insights into the Impact of Heterogeneous Glycosylation on the Pharmacokinetic Behavior of Follistatin-Fc-Based BiotherapeuticsAmita Datta-Mannan, Lihua Huang, Jennifer Pereira, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|October 20, 2006
Humanized IgG1 variants with differential binding properties to the neonatal Fc receptor: relationship to pharmacokinetics in mice and primatesAmita Datta-Mannan, Derrick R Witcher, Ying Tang, et al.
The AAPS Journal|September 27, 2018
The Properties of Cysteine-Conjugated Antibody-Drug Conjugates Are Impacted by the IgG SubclassAmita Datta-Mannan, Hiuwan Choi, David Stokell, et al.
Antibodies (Basel, Switzerland)|January 16, 2020
Antibody Conjugates-Recent Advances and Future InnovationsDonmienne Leung, Jacqueline M Wurst, Tao Liu, et al.
Mabs|April 26, 2016
Aberrant bispecific antibody pharmacokinetics linked to liver sinusoidal endothelium clearance mechanism in cynomolgus monkeysAmita Datta-Mannan, Johnny E Croy, Linda Schirtzinger, et al.
Mabs|September 5, 2015
The interplay of non-specific binding, target-mediated clearance and FcRn interactions on the pharmacokinetics of humanized antibodiesAmita Datta-Mannan, Jirong Lu, Derrick R Witcher, et al.
Bioorganic & Medicinal Chemistry|January 18, 2021
Influence of FcRn binding properties on the gastrointestinal absorption and exposure profile of Fc moleculesScott A Lawrence, Ross Blankenship, Robin Brown, et al.
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