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Drug Metabolism and Disposition: the Biological Fate of Chemicals|July 21, 2012
Acetylenic linkers in lead compounds: a study of the stability of the propargyl-linked antifolatesWangda Zhou, Kishore Viswanathan, Dennis Hill, et al.Bioorganic & Medicinal Chemistry|March 12, 2014
Studies on the antiproliferative effects of tropolone derivatives in Jurkat T-lymphocyte cellsSophia N Ononye, Michael D Vanheyst, Charles Giardina, et al.Pharmaceutical Patent Analyst|October 29, 2013
Toward isozyme-selective inhibitors of histone deacetylase as therapeutic agents for the treatment of cancerSophia N Ononye, Michael van Heyst, Eric M Falcone, et al.Eukaryotic Cell|January 27, 2009
Towards new antifolates targeting eukaryotic opportunistic infectionsJieying Liu, David B Bolstad, Erin S D Bolstad, et al.Journal of Medicinal Chemistry|October 7, 2008
Structure-based approach to the development of potent and selective inhibitors of dihydrofolate reductase from cryptosporidiumDavid B Bolstad, Erin S D Bolstad, Kathleen M Frey, et al.Pharmacological Research|September 25, 2016
Novel α-substituted tropolones promote potent and selective caspase-dependent leukemia cell apoptosisJin Li, Eric R Falcone, Sarah A Holstein, et al.Biochemistry|April 15, 2015
Measuring propargyl-linked drug populations inside bacterial cells, and their interaction with a dihydrofolate reductase target, by Raman microscopyHossein Heidari-Torkabadi, Tao Che, Michael N Lombardo, et al.Journal of Molecular Biology|March 3, 2009
Crystal structures of wild-type and mutant methicillin-resistant Staphylococcus aureus dihydrofolate reductase reveal an alternate conformation of NADPH that may be linked to trimethoprim resistanceKathleen M Frey, Jieying Liu, Michael N Lombardo, et al.Antimicrobial Agents and Chemotherapy|October 8, 2014
Crystal structures of Klebsiella pneumoniae dihydrofolate reductase bound to propargyl-linked antifolates reveal features for potency and selectivityKristen M Lamb, Michael N Lombardo, Jeremy Alverson, et al.Organic Letters|December 14, 2016
Direct Substitution of Arylalkynyl Carbinols Provides Access to Diverse Terminal Acetylene Building BlocksNarendran G-Dayanandan, Eric W Scocchera, Santosh Keshipeddy, et al.Pageof 12