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Proceedings of the National Academy of Sciences of the United States of America
|
July 21, 2010
Predicting resistance mutations using protein design algorithms
Kathleen M Frey, Ivelin Georgiev, Bruce R Donald, et al.
Antimicrobial Agents and Chemotherapy
|
April 12, 2012
Prospective screening of novel antibacterial inhibitors of dihydrofolate reductase for mutational resistance
Kathleen M Frey, Kishore Viswanathan, Dennis L Wright, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
February 21, 2009
Computational structure-based redesign of enzyme activity
Cheng-Yu Chen, Ivelin Georgiev, Amy C Anderson, et al.
Bioorganic & Medicinal Chemistry Letters
|
February 5, 2013
Structural analysis of the active sites of dihydrofolate reductase from two species of Candida uncovers ligand-induced conformational changes shared among species
Janet L Paulsen, Kishore Viswanathan, Dennis L Wright, et al.
Expert Opinion on Therapeutic Patents
|
June 18, 2010
Dihydrofolate reductase inhibitors: developments in antiparasitic chemotherapy
David B Bolstad, Erin Sd Bolstad, Dennis L Wright, et al.
Drug Discovery Today
|
July 26, 2011
The challenge of developing robust drugs to overcome resistance
Amy C Anderson, Michael P Pollastri, Celia A Schiffer, et al.
Journal of Computational Biology : a Journal of Computational Molecular Cell Biology
|
August 20, 2005
A novel ensemble-based scoring and search algorithm for protein redesign and its application to modify the substrate specificity of the gramicidin synthetase a phenylalanine adenylation enzyme
Ryan H Lilien, Brian W Stevens, Amy C Anderson, et al.
Biochemistry
|
September 24, 2013
Elucidating features that drive the design of selective antifolates using crystal structures of human dihydrofolate reductase
Kristen M Lamb, Narendran G-Dayanandan, Dennis L Wright, et al.
ACS Infectious Diseases
|
September 15, 2016
Crystal Structures of Trimethoprim-Resistant DfrA1 Rationalize Potent Inhibition by Propargyl-Linked Antifolates
Michael N Lombardo, Narendran G-Dayanandan, Dennis L Wright, et al.
Journal of Structural Biology
|
December 23, 2009
Towards the understanding of resistance mechanisms in clinically isolated trimethoprim-resistant, methicillin-resistant Staphylococcus aureus dihydrofolate reductase
Kathleen M Frey, Michael N Lombardo, Dennis L Wright, et al.
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of 8
Search research articles
Search
Showing results (21-30 of 71) with videos related to
Sort By:
Page
of 8
Proceedings of the National Academy of Sciences of the United States of America
|
July 21, 2010
Predicting resistance mutations using protein design algorithms
Kathleen M Frey, Ivelin Georgiev, Bruce R Donald, et al.
Antimicrobial Agents and Chemotherapy
|
April 12, 2012
Prospective screening of novel antibacterial inhibitors of dihydrofolate reductase for mutational resistance
Kathleen M Frey, Kishore Viswanathan, Dennis L Wright, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
February 21, 2009
Computational structure-based redesign of enzyme activity
Cheng-Yu Chen, Ivelin Georgiev, Amy C Anderson, et al.
Bioorganic & Medicinal Chemistry Letters
|
February 5, 2013
Structural analysis of the active sites of dihydrofolate reductase from two species of Candida uncovers ligand-induced conformational changes shared among species
Janet L Paulsen, Kishore Viswanathan, Dennis L Wright, et al.
Expert Opinion on Therapeutic Patents
|
June 18, 2010
Dihydrofolate reductase inhibitors: developments in antiparasitic chemotherapy
David B Bolstad, Erin Sd Bolstad, Dennis L Wright, et al.
Drug Discovery Today
|
July 26, 2011
The challenge of developing robust drugs to overcome resistance
Amy C Anderson, Michael P Pollastri, Celia A Schiffer, et al.
Journal of Computational Biology : a Journal of Computational Molecular Cell Biology
|
August 20, 2005
A novel ensemble-based scoring and search algorithm for protein redesign and its application to modify the substrate specificity of the gramicidin synthetase a phenylalanine adenylation enzyme
Ryan H Lilien, Brian W Stevens, Amy C Anderson, et al.
Biochemistry
|
September 24, 2013
Elucidating features that drive the design of selective antifolates using crystal structures of human dihydrofolate reductase
Kristen M Lamb, Narendran G-Dayanandan, Dennis L Wright, et al.
ACS Infectious Diseases
|
September 15, 2016
Crystal Structures of Trimethoprim-Resistant DfrA1 Rationalize Potent Inhibition by Propargyl-Linked Antifolates
Michael N Lombardo, Narendran G-Dayanandan, Dennis L Wright, et al.
Journal of Structural Biology
|
December 23, 2009
Towards the understanding of resistance mechanisms in clinically isolated trimethoprim-resistant, methicillin-resistant Staphylococcus aureus dihydrofolate reductase
Kathleen M Frey, Michael N Lombardo, Dennis L Wright, et al.
Page
of 8