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Nature Communications|February 1, 2017
SC83288 is a clinical development candidate for the treatment of severe malariaStefano Pegoraro, Maëlle Duffey, Thomas D Otto, et al.European Journal of Medicinal Chemistry|February 20, 2021
Structure activity refinement of phenylsulfonyl piperazines as antimalarials that block erythrocytic invasionWilliam Nguyen, Madeline G Dans, Anna Ngo, et al.RSC Medicinal Chemistry|February 19, 2025
Heterocyclic core modifications in trypanosomacidal 2-[(phenylheteroaryl)ethyl]ureasArthur Toynton, Lori Ferrins, Harriet L Newson, et al.ACS Medicinal Chemistry Letters|March 19, 2020
Discovery of Potent N-Ethylurea Pyrazole Derivatives as Dual Inhibitors of Trypanosoma brucei and Trypanosoma cruziSwapna Varghese, Raphaël Rahmani, Stephanie Russell, et al.European Journal of Medicinal Chemistry|June 7, 2014
Discovery of HDAC inhibitors with potent activity against multiple malaria parasite life cycle stagesFinn K Hansen, Subathdrage D M Sumanadasa, Katharina Stenzel, et al.The Journal of Clinical Investigation|February 12, 2020
A Plasmodium vivax experimental human infection model for evaluating efficacy of interventionsKatharine A Collins, Claire Yt Wang, Matthew Adams, et al.Malaria Journal|April 16, 2014
Repositioning: the fast track to new anti-malarial medicines?Julie Lotharius, Francisco Javier Gamo-Benito, Iñigo Angulo-Barturen, et al.Antimicrobial Agents and Chemotherapy|May 6, 2015
Splenic retention of Plasmodium falciparum gametocytes to block the transmission of malariaJulien Duez, John P Holleran, Papa Alioune Ndour, et al.Journal of Medicinal Chemistry|June 28, 2017
3-Hydroxy-N'-arylidenepropanehydrazonamides with Halo-Substituted Phenanthrene Scaffolds Cure P. berghei Infected Mice When Administered PerorallyMichael Leven, Tanja C Knaab, Jana Held, et al.European Journal of Medicinal Chemistry|February 23, 2024
Novel aroyl guanidine anti-trypanosomal compounds that exert opposing effects on parasite energy metabolismSwapna Varghese, Anubhav Srivastava, Siu Wai Wong, et al.Pageof 22