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Journal of Medicinal Chemistry|February 27, 2014
Medicinal chemistry optimization of antiplasmodial imidazopyridazine hits from high throughput screening of a SoftFocus kinase library: part 1Claire Le Manach, Diego Gonzàlez Cabrera, Frederic Douelle, et al.Antimicrobial Agents and Chemotherapy|April 16, 2014
Lysine acetylation in sexual stage malaria parasites is a target for antimalarial small moleculesKatharine Trenholme, Linda Marek, Sandra Duffy, et al.Elife|July 8, 2024
Chemoproteomics validates selective targeting of Plasmodium M1 alanyl aminopeptidase as an antimalarial strategyCarlo Giannangelo, Matthew P Challis, Ghizal Siddiqui, et al.Journal of Medicinal Chemistry|September 16, 2022
Nitroimidazopyrazinones with Oral Activity against Tuberculosis and Chagas Disease in Mouse Models of InfectionChee Wei Ang, Brendon M Lee, Colin J Jackson, et al.Organic & Biomolecular Chemistry|June 27, 2019
The cubane paradigm in bioactive molecule discovery: further scope, limitations and the cyclooctatetraene complementSevan D Houston, Tyler Fahrenhorst-Jones, Hui Xing, et al.Journal of Medicinal Chemistry|January 13, 2017
Optimization of 2-Anilino 4-Amino Substituted Quinazolines into Potent Antimalarial Agents with Oral in Vivo ActivityPaul R Gilson, Cyrus Tan, Kate E Jarman, et al.Bioorganic Chemistry|October 24, 2021
Property activity refinement of 2-anilino 4-amino substituted quinazolines as antimalarials with fast acting asexual parasite activityTrent D Ashton, Anna Ngo, Paola Favuzza, et al.Antimicrobial Agents and Chemotherapy|August 30, 2021
The Novel bis-1,2,4-Triazine MIPS-0004373 Demonstrates Rapid and Potent Activity against All Blood Stages of the Malaria ParasiteKatherine M Ellis, Leonardo Lucantoni, Marina Chavchich, et al.Journal of Medicinal Chemistry|January 30, 2014
Euodenine A: a small-molecule agonist of human TLR4Juliette E Neve, Hasanthi P Wijesekera, Sandra Duffy, et al.European Journal of Medicinal Chemistry|October 2, 2020
Re-evaluating pretomanid analogues for Chagas disease: Hit-to-lead studies reveal both in vitro and in vivo trypanocidal efficacyAndrew M Thompson, Patrick D O'Connor, Andrew J Marshall, et al.Pageof 22