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Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
November 3, 2020
Considerations from the Innovation and Quality Induction Working Group in Response to Drug-Drug Interaction Guidance from Regulatory Agencies: Guidelines on Model Fitting and Recommendations on Time Course for In Vitro Cytochrome P450 Induction Studies Including Impact on Drug Interaction Risk Assessment
Simon G Wong, Diane Ramsden, Shannon Dallas, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
July 1, 2018
Considerations from the Innovation and Quality Induction Working Group in Response to Drug-Drug Interaction Guidances from Regulatory Agencies: Focus on CYP3A4 mRNA In Vitro Response Thresholds, Variability, and Clinical Relevance
Jane R Kenny, Diane Ramsden, David B Buckley, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
June 25, 2017
Considerations from the IQ Induction Working Group in Response to Drug-Drug Interaction Guidance from Regulatory Agencies: Focus on Downregulation, CYP2C Induction, and CYP2B6 Positive Control
Niresh Hariparsad, Diane Ramsden, Jairam Palamanda, et al.
Free Radical Biology & Medicine
|
May 22, 2023
Suppression of superoxide/hydrogen peroxide production at mitochondrial site I<sub>Q</sub> decreases fat accumulation, improves glucose tolerance and normalizes fasting insulin concentration in mice fed a high-fat diet
Mark A Watson, Harmanmeet Brar, Edwin T Gibbs, et al.
Journal of Medicinal Chemistry
|
March 6, 2023
Discovery of a Potent Chloroacetamide GPX4 Inhibitor with Bioavailability to Enable Target Engagement in Mice, a Potential Tool Compound for Inducing Ferroptosis <i>In Vivo</i>
John T Randolph, Matthew J O'Connor, Fei Han, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
January 9, 2019
AWZ1066S, a highly specific anti-<i>Wolbachia</i> drug candidate for a short-course treatment of filariasis
W David Hong, Farid Benayoud, Gemma L Nixon, et al.
Cancer Discovery
|
July 12, 2018
Discovery of Selective Estrogen Receptor Covalent Antagonists for the Treatment of ERα<sup>WT</sup> and ERα<sup>MUT</sup> Breast Cancer
Xiaoling Puyang, Craig Furman, Guo Zhu Zheng, et al.
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of 2
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Showing results (11-20 of 17) with videos related to
Sort By:
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This site can display upto 17 results.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
November 3, 2020
Considerations from the Innovation and Quality Induction Working Group in Response to Drug-Drug Interaction Guidance from Regulatory Agencies: Guidelines on Model Fitting and Recommendations on Time Course for In Vitro Cytochrome P450 Induction Studies Including Impact on Drug Interaction Risk Assessment
Simon G Wong, Diane Ramsden, Shannon Dallas, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
July 1, 2018
Considerations from the Innovation and Quality Induction Working Group in Response to Drug-Drug Interaction Guidances from Regulatory Agencies: Focus on CYP3A4 mRNA In Vitro Response Thresholds, Variability, and Clinical Relevance
Jane R Kenny, Diane Ramsden, David B Buckley, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
June 25, 2017
Considerations from the IQ Induction Working Group in Response to Drug-Drug Interaction Guidance from Regulatory Agencies: Focus on Downregulation, CYP2C Induction, and CYP2B6 Positive Control
Niresh Hariparsad, Diane Ramsden, Jairam Palamanda, et al.
Free Radical Biology & Medicine
|
May 22, 2023
Suppression of superoxide/hydrogen peroxide production at mitochondrial site I<sub>Q</sub> decreases fat accumulation, improves glucose tolerance and normalizes fasting insulin concentration in mice fed a high-fat diet
Mark A Watson, Harmanmeet Brar, Edwin T Gibbs, et al.
Journal of Medicinal Chemistry
|
March 6, 2023
Discovery of a Potent Chloroacetamide GPX4 Inhibitor with Bioavailability to Enable Target Engagement in Mice, a Potential Tool Compound for Inducing Ferroptosis <i>In Vivo</i>
John T Randolph, Matthew J O'Connor, Fei Han, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
January 9, 2019
AWZ1066S, a highly specific anti-<i>Wolbachia</i> drug candidate for a short-course treatment of filariasis
W David Hong, Farid Benayoud, Gemma L Nixon, et al.
Cancer Discovery
|
July 12, 2018
Discovery of Selective Estrogen Receptor Covalent Antagonists for the Treatment of ERα<sup>WT</sup> and ERα<sup>MUT</sup> Breast Cancer
Xiaoling Puyang, Craig Furman, Guo Zhu Zheng, et al.
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of 2