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Plos Neglected Tropical Diseases|January 17, 2012
Integrated dataset of screening hits against multiple neglected disease pathogensSolomon Nwaka, Dominique Besson, Bernadette Ramirez, et al.
Chemical Biology & Drug Design|March 21, 2022
Semisynthetic triterpenes led to the generation of selective antitrypanosomal lead compoundsFernanda Guilhon-Simplicio, Carlos Klinger Rodrigues Serrão, Ana Cristina da Silva Pinto, et al.
ACS Infectious Diseases|December 12, 2024
Discovery and Development of an Advanced Lead for the Treatment of African TrypanosomiasisKayhan Ilbeigi, Dorien Mabille, An Matheeussen, et al.
ACS Infectious Diseases|July 7, 2023
Structure-Property Optimization of a Series of Imidazopyridines for Visceral LeishmaniasisMaria Dichiara, Quillon J Simpson, Antonio Quotadamo, et al.
European Journal of Medicinal Chemistry|December 2, 2022
Hit-to-lead optimization of a 2-aminobenzimidazole series as new candidates for chagas diseaseCelso de Oliveira Rezende Júnior, Pablo David Grigol Martinez, Rafael Augusto Alves Ferreira, et al.
The Journal of Antimicrobial Chemotherapy|December 21, 2019
Evaluation of phthalazinone phosphodiesterase inhibitors with improved activity and selectivity against Trypanosoma cruziJulianna Siciliano De Araújo, Patrícia Bernardino da Silva, Marcos Meuser Batista, et al.
Plos Neglected Tropical Diseases|February 22, 2021
2-aminobenzimidazoles for leishmaniasis: From initial hit discovery to in vivo profilingRafael Augusto Alves Ferreira, Celso de Oliveira Rezende Junior, Pablo David Grigol Martinez, et al.
Journal of Medicinal Chemistry|April 20, 2018
Targeting a Subpocket in Trypanosoma brucei Phosphodiesterase B1 (TbrPDEB1) Enables the Structure-Based Discovery of Selective Inhibitors with Trypanocidal ActivityAntoni R Blaazer, Abhimanyu K Singh, Erik de Heuvel, et al.
Science Translational Medicine|December 13, 2023
DNDI-6174 is a preclinical candidate for visceral leishmaniasis that targets the cytochrome bc1Stéphanie Braillard, Martine Keenan, Karen J Breese, et al.
ACS Infectious Diseases|August 11, 2025
Collaborative Synthesis for Neglected Diseases through the Open Synthesis Network: Structure-Activity Relationships of Arylaminopyrazoles as Chagas Disease TreatmentsZigli Abdulai, Natasha Agbo, Jonathan I Anderson, et al.
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