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Frontiers in Genome Editing|January 6, 2023
Efficient and error-free correction of sickle mutation in human erythroid cells using prime editor-2Anila George, Nithin Sam Ravi, Kirti Prasad, et al.
Frontiers in Pharmacology|June 16, 2023
Modulating retinoid-X-receptor alpha (RXRA) expression sensitizes chronic myeloid leukemia cells to imatinib in vitro and reduces disease burden in vivoBharathi M Rajamani, Raveen Stephen Stallon Illangeswaran, Esther Sathya Bama Benjamin, et al.
Pharmacogenomics and Personalized Medicine|October 11, 2021
NUDT15 c.415C>T Polymorphism Predicts 6-MP Induced Early Myelotoxicity in Patients with Acute Lymphoblastic Leukemia Undergoing Maintenance TherapyAswin Anand Pai, Ajith Mohan, Esther Sathya Bama Benjamin, et al.
Molecular Therapy. Nucleic Acids|May 31, 2024
Precise correction of a spectrum of β-thalassemia mutations in coding and non-coding regions by base editorsKirti Prasad, Nivedhitha Devaraju, Anila George, et al.
Clinical Pharmacology and Therapeutics|October 17, 2023
Treosulfan Exposure Predicts Thalassemia-Free Survival in Patients with Beta Thalassemia Major Undergoing Allogeneic Hematopoietic Cell TransplantationAswin Anand Pai, Ezhilpavai Mohanan, John C Panetta, et al.
Ejhaem|September 5, 2020
Prognostic plasma biomarkers of early complications and graft-versus-host disease in patients undergoing allogeneic hematopoietic stem cell transplantationBalaji Balakrishnan, Raveen Stephen Stallon Illangeswaran, Bharathi M Rajamani, et al.
Molecular Therapy : the Journal of the American Society of Gene Therapy|January 26, 2024
Base editing of key residues in the BCL11A-XL-specific zinc finger domains derepresses fetal globin expressionVignesh Rajendiran, Nivedhitha Devaraju, Mahdi Haddad, et al.
Molecular Therapy. Nucleic Acids|May 22, 2023
Editing the core region in HPFH deletions alters fetal and adult globin expression for treatment of β-hemoglobinopathiesVigneshwaran Venkatesan, Abisha Crystal Christopher, Manuel Rhiel, et al.
Elife|February 11, 2022
Identification of novel HPFH-like mutations by CRISPR base editing that elevate the expression of fetal hemoglobinNithin Sam Ravi, Beeke Wienert, Stacia K Wyman, et al.
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