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Proceedings of the National Academy of Sciences of the United States of America
|
January 10, 2002
HIV-1 escape from a small molecule, CCR5-specific entry inhibitor does not involve CXCR4 use
Alexandra Trkola, Shawn E Kuhmann, Julie M Strizki, et al.
ACS Medicinal Chemistry Letters
|
August 18, 2022
Discovery of MK-1462: GLP-1 and Glucagon Receptor Dual Agonist for the Treatment of Obesity and Diabetes
Anandan Palani, Andrea R Nawrocki, Federica Orvieto, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 21, 2012
The discovery of fused oxadiazepines as gamma secretase modulators for treatment of Alzheimer's disease
Hongmei Li, Jun Qin, Pawan Dhondi, et al.
Bioorganic & Medicinal Chemistry Letters
|
February 22, 2014
Quality by design (QbD) of amide isosteres: 5,5-Disubstituted isoxazolines as potent CRTh2 antagonists with favorable pharmacokinetic and drug-like properties
Dong Xiao, Xiaohong Zhu, Younong Yu, et al.
ACS Medicinal Chemistry Letters
|
June 6, 2014
Discovery of a potent nicotinic Acid receptor agonist for the treatment of dyslipidemia
Jun Qin, Ashwin Rao, Xiao Chen, et al.
ACS Medicinal Chemistry Letters
|
July 14, 2026
Discovery of Biased Dual-Agonists of Glucagon-Like Peptide 1 and Glucagon Receptors through Mutation of a Conserved Aspartate
Robert E Thompson, Aditya J Desai, Dmitri Pissarnitski, et al.
ACS Medicinal Chemistry Letters
|
June 6, 2014
Synthesis and SAR Studies of Fused Oxadiazines as γ-Secretase Modulators for Treatment of Alzheimer's Disease
Xianhai Huang, Wei Zhou, Xiaoxiang Liu, et al.
ACS Medicinal Chemistry Letters
|
November 19, 2021
Comprehensive Strategies to Bicyclic Prolines: Applications in the Synthesis of Potent Arginase Inhibitors
Derun Li, Hongjun Zhang, Thomas W Lyons, et al.
ACS Medicinal Chemistry Letters
|
September 16, 2021
Structure-Based Discovery of Proline-Derived Arginase Inhibitors with Improved Oral Bioavailability for Immuno-Oncology
Min Lu, Hongjun Zhang, Derun Li, et al.
ACS Medicinal Chemistry Letters
|
April 16, 2020
Discovery and Optimization of Rationally Designed Bicyclic Inhibitors of Human Arginase to Enhance Cancer Immunotherapy
Matthew J Mitcheltree, Derun Li, Abdelghani Achab, et al.
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Search research articles
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Showing results (41-50 of 56) with videos related to
Sort By:
Page
of 6
Proceedings of the National Academy of Sciences of the United States of America
|
January 10, 2002
HIV-1 escape from a small molecule, CCR5-specific entry inhibitor does not involve CXCR4 use
Alexandra Trkola, Shawn E Kuhmann, Julie M Strizki, et al.
ACS Medicinal Chemistry Letters
|
August 18, 2022
Discovery of MK-1462: GLP-1 and Glucagon Receptor Dual Agonist for the Treatment of Obesity and Diabetes
Anandan Palani, Andrea R Nawrocki, Federica Orvieto, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 21, 2012
The discovery of fused oxadiazepines as gamma secretase modulators for treatment of Alzheimer's disease
Hongmei Li, Jun Qin, Pawan Dhondi, et al.
Bioorganic & Medicinal Chemistry Letters
|
February 22, 2014
Quality by design (QbD) of amide isosteres: 5,5-Disubstituted isoxazolines as potent CRTh2 antagonists with favorable pharmacokinetic and drug-like properties
Dong Xiao, Xiaohong Zhu, Younong Yu, et al.
ACS Medicinal Chemistry Letters
|
June 6, 2014
Discovery of a potent nicotinic Acid receptor agonist for the treatment of dyslipidemia
Jun Qin, Ashwin Rao, Xiao Chen, et al.
ACS Medicinal Chemistry Letters
|
July 14, 2026
Discovery of Biased Dual-Agonists of Glucagon-Like Peptide 1 and Glucagon Receptors through Mutation of a Conserved Aspartate
Robert E Thompson, Aditya J Desai, Dmitri Pissarnitski, et al.
ACS Medicinal Chemistry Letters
|
June 6, 2014
Synthesis and SAR Studies of Fused Oxadiazines as γ-Secretase Modulators for Treatment of Alzheimer's Disease
Xianhai Huang, Wei Zhou, Xiaoxiang Liu, et al.
ACS Medicinal Chemistry Letters
|
November 19, 2021
Comprehensive Strategies to Bicyclic Prolines: Applications in the Synthesis of Potent Arginase Inhibitors
Derun Li, Hongjun Zhang, Thomas W Lyons, et al.
ACS Medicinal Chemistry Letters
|
September 16, 2021
Structure-Based Discovery of Proline-Derived Arginase Inhibitors with Improved Oral Bioavailability for Immuno-Oncology
Min Lu, Hongjun Zhang, Derun Li, et al.
ACS Medicinal Chemistry Letters
|
April 16, 2020
Discovery and Optimization of Rationally Designed Bicyclic Inhibitors of Human Arginase to Enhance Cancer Immunotherapy
Matthew J Mitcheltree, Derun Li, Abdelghani Achab, et al.
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of 6