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American Journal of Respiratory Cell and Molecular Biology|June 2, 2007
Restoration of W1282X CFTR activity by enhanced expressionSteven M Rowe, Karoly Varga, Andras Rab, et al.American Journal of Respiratory Cell and Molecular Biology|February 3, 2007
VCP/p97 AAA-ATPase does not interact with the endogenous wild-type cystic fibrosis transmembrane conductance regulatorRebecca F Goldstein, Ashutosh Niraj, Todd P Sanderson, et al.The Journal of Biological Chemistry|October 18, 2011
The unfolded protein response (UPR)-activated transcription factor X-box-binding protein 1 (XBP1) induces microRNA-346 expression that targets the human antigen peptide transporter 1 (TAP1) mRNA and governs immune regulatory genesRafal Bartoszewski, Joseph W Brewer, Andras Rab, et al.The Journal of Biological Chemistry|September 10, 2023
Elexacaftor/VX-445-mediated CFTR interactome remodeling reveals differential correction driven by mutation-specific translational dynamicsMinsoo Kim, Eli Fritz McDonald, Carleen Mae P Sabusap, et al.Biorxiv : the Preprint Server for Biology|February 13, 2023
Elexacaftor/VX-445-mediated CFTR interactome remodeling reveals differential correction driven by mutation-specific translational dynamicsMinsoo Kim, Eli Fritz McDonald, Carleen Mae P Sabusap, et al.The Journal of Biological Chemistry|March 30, 2021
The CFTR P67L variant reveals a key role for N-terminal lasso helices in channel folding, maturation, and pharmacologic rescueCarleen Mae Sabusap, Disha Joshi, Luba Simhaev, et al.Nature Communications|April 5, 2024
Translation velocity determines the efficacy of engineered suppressor tRNAs on pathogenic nonsense mutationsNikhil Bharti, Leonardo Santos, Marcos Davyt, et al.Journal of Chemical Information and Modeling|March 15, 2021
Stability Prediction for Mutations in the Cytosolic Domains of Cystic Fibrosis Transmembrane Conductance RegulatorMalkeet Singh Bahia, Netaly Khazanov, Qingxian Zhou, et al.Npj Drug Discovery|July 1, 2026
A novel drug series optimized to address cystic fibrosis and other CFTR deficiency diseases of human airwaysAndras Rab, Jeong S Hong, Candela Manfredi, et al.FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology|August 3, 2013
The silent codon change I507-ATC->ATT contributes to the severity of the ΔF508 CFTR channel dysfunctionAhmed Lazrak, Lianwu Fu, Vedrana Bali, et al.Pageof 4