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Frontiers in Cellular Neuroscience|March 23, 2017
The GABAergic Hypothesis for Cognitive Disabilities in Down SyndromeAndrea Contestabile, Salvatore Magara, Laura CanceddaNature Communications|May 9, 2013
Non-hyperpolarizing GABAB receptor activation regulates neuronal migration and neurite growth and specification by cAMP/LKB1Guillaume Bony, Joanna Szczurkowska, Ilaria Tamagno, et al.Nature Medicine|March 17, 2015
Reversing excitatory GABAAR signaling restores synaptic plasticity and memory in a mouse model of Down syndromeGabriele Deidda, Martina Parrini, Shovan Naskar, et al.Neuron|May 29, 2024
Integrative multi-omic analysis reveals conserved cell-projection deficits in human Down syndrome brainsMohit Rastogi, Martina Bartolucci, Marina Nanni, et al.Scientific Reports|December 6, 2017
Aerobic exercise and a BDNF-mimetic therapy rescue learning and memory in a mouse model of Down syndromeMartina Parrini, Diego Ghezzi, Gabriele Deidda, et al.Frontiers in Neuroscience|September 26, 2019
Gene Editing Preserves Visual Functions in a Mouse Model of Retinal DegenerationPaola Vagni, Laura E Perlini, Naïg A L Chenais, et al.Iscience|March 28, 2024
Heterogeneous subpopulations of GABAAR-responding neurons coexist across neuronal network scales and developmental stages in health and diseaseIlaria Colombi, Mohit Rastogi, Martina Parrini, et al.Journal of Medicinal Chemistry|June 17, 2021
Design, Synthesis, In Vitro and In Vivo Characterization of Selective NKCC1 Inhibitors for the Treatment of Core Symptoms in Down SyndromeMarco Borgogno, Annalisa Savardi, Jacopo Manigrasso, et al.Neuron|October 7, 2020
Rescuing Over-activated Microglia Restores Cognitive Performance in Juvenile Animals of the Dp(16) Mouse Model of Down SyndromeBruno Pinto, Giovanni Morelli, Mohit Rastogi, et al.Chem|August 21, 2020
Discovery of a Small Molecule Drug Candidate for Selective NKCC1 Inhibition in Brain DisordersAnnalisa Savardi, Marco Borgogno, Roberto Narducci, et al.Pageof 10