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Angewandte Chemie (International Ed. in English)
|
September 17, 2013
Dynamic nuclear polarization NMR spectroscopy: revealing multiple conformations in lipid-anchored peptide vaccines
Eline J Koers, Maria Pilar López-Deber, Markus Weingarth, et al.
Bioorganic & Medicinal Chemistry
|
November 28, 2021
Structure-activity relationship around PI-2620 highlights the importance of the nitrogen atom position in the tricyclic core
Heiko Kroth, Felix Oden, Andreia Monica Serra, et al.
Molecular Therapy : the Journal of the American Society of Gene Therapy
|
June 16, 2025
A single dose of a vectorized mAb targeting TDP-43 potently inhibits the neuropathology in a model of ALS/FTD
Greg Del Val, Florence Gauye, Mickaël Audrain, et al.
Journal of Medicinal Chemistry
|
August 30, 2021
<b>PI-2620</b> Lead Optimization Highlights the Importance of Off-Target Assays to Develop a PET Tracer for the Detection of Pathological Aggregated Tau in Alzheimer's Disease and Other Tauopathies
Heiko Kroth, Felix Oden, Jerome Molette, et al.
Journal of Alzheimer'S Disease : JAD
|
September 28, 2013
Increased efflux of amyloid-β peptides through the blood-brain barrier by muscarinic acetylcholine receptor inhibition reduces pathological phenotypes in mouse models of brain amyloidosis
Paolo Paganetti, Katia Antoniello, Kavi Devraj, et al.
European Journal of Medicinal Chemistry
|
August 11, 2020
Discovery of 2-(4-(2-fluoroethoxy)piperidin-1-yl)-9-methyl-9H-pyrrolo[2,3-b:4,5-c']dipyridine ([18F]PI-2014) as PET tracer for the detection of pathological aggregated tau in Alzheimer's disease and other tauopathies
Emanuele Gabellieri, Francesca Capotosti, Jerome Molette, et al.
Mabs
|
July 6, 2023
Improved antibody pharmacokinetics by disruption of contiguous positive surface potential and charge reduction using alternate human framework
Romain Ollier, Aline Fuchs, Florence Gauye, et al.
Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine
|
November 13, 2019
Tau PET imaging with <sup>18</sup>F-PI-2620 in Patients with Alzheimer Disease and Healthy Controls: A First-in-Humans Study
Andre Mueller, Santiago Bullich, Olivier Barret, et al.
Plos One
|
August 27, 2013
Efficacy and safety of a liposome-based vaccine against protein Tau, assessed in tau.P301L mice that model tauopathy
Clara Theunis, Natalia Crespo-Biel, Valérie Gafner, et al.
Scientific Reports
|
December 21, 2016
Structure of Crenezumab Complex with Aβ Shows Loss of β-Hairpin
Mark Ultsch, Bing Li, Till Maurer, et al.
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of 6
Search research articles
Search
Showing results (21-30 of 51) with videos related to
Sort By:
Page
of 6
Angewandte Chemie (International Ed. in English)
|
September 17, 2013
Dynamic nuclear polarization NMR spectroscopy: revealing multiple conformations in lipid-anchored peptide vaccines
Eline J Koers, Maria Pilar López-Deber, Markus Weingarth, et al.
Bioorganic & Medicinal Chemistry
|
November 28, 2021
Structure-activity relationship around PI-2620 highlights the importance of the nitrogen atom position in the tricyclic core
Heiko Kroth, Felix Oden, Andreia Monica Serra, et al.
Molecular Therapy : the Journal of the American Society of Gene Therapy
|
June 16, 2025
A single dose of a vectorized mAb targeting TDP-43 potently inhibits the neuropathology in a model of ALS/FTD
Greg Del Val, Florence Gauye, Mickaël Audrain, et al.
Journal of Medicinal Chemistry
|
August 30, 2021
<b>PI-2620</b> Lead Optimization Highlights the Importance of Off-Target Assays to Develop a PET Tracer for the Detection of Pathological Aggregated Tau in Alzheimer's Disease and Other Tauopathies
Heiko Kroth, Felix Oden, Jerome Molette, et al.
Journal of Alzheimer'S Disease : JAD
|
September 28, 2013
Increased efflux of amyloid-β peptides through the blood-brain barrier by muscarinic acetylcholine receptor inhibition reduces pathological phenotypes in mouse models of brain amyloidosis
Paolo Paganetti, Katia Antoniello, Kavi Devraj, et al.
European Journal of Medicinal Chemistry
|
August 11, 2020
Discovery of 2-(4-(2-fluoroethoxy)piperidin-1-yl)-9-methyl-9H-pyrrolo[2,3-b:4,5-c']dipyridine ([18F]PI-2014) as PET tracer for the detection of pathological aggregated tau in Alzheimer's disease and other tauopathies
Emanuele Gabellieri, Francesca Capotosti, Jerome Molette, et al.
Mabs
|
July 6, 2023
Improved antibody pharmacokinetics by disruption of contiguous positive surface potential and charge reduction using alternate human framework
Romain Ollier, Aline Fuchs, Florence Gauye, et al.
Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine
|
November 13, 2019
Tau PET imaging with <sup>18</sup>F-PI-2620 in Patients with Alzheimer Disease and Healthy Controls: A First-in-Humans Study
Andre Mueller, Santiago Bullich, Olivier Barret, et al.
Plos One
|
August 27, 2013
Efficacy and safety of a liposome-based vaccine against protein Tau, assessed in tau.P301L mice that model tauopathy
Clara Theunis, Natalia Crespo-Biel, Valérie Gafner, et al.
Scientific Reports
|
December 21, 2016
Structure of Crenezumab Complex with Aβ Shows Loss of β-Hairpin
Mark Ultsch, Bing Li, Till Maurer, et al.
Page
of 6