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ACS Medicinal Chemistry Letters|March 25, 2017
Discovery of Potent, Selective, and Structurally Novel Dot1L Inhibitors by a Fragment Linking ApproachHenrik Möbitz, Rainer Machauer, Philipp Holzer, et al.Chemmedchem|May 9, 2019
Structural States of Hdm2 and HdmX: X-ray Elucidation of Adaptations and Binding Interactions for Different Chemical Compound ClassesJoerg Kallen, Aude Izaac, Suzanne Chau, et al.Bioorganic & Medicinal Chemistry Letters|March 9, 2016
Optimisation of a 5-[3-phenyl-(2-cyclic-ether)-methyl-ether]-4-aminopyrrolopyrimidine series of IGF-1R inhibitorsRobin A Fairhurst, Thomas H Marsilje, Stefan Stutz, et al.Journal of Medicinal Chemistry|July 10, 2025
Promise and Challenge of β-Lactone Electrophiles to Target Aspartate 12 of Mutant KRASG12DBalázs Budai, Andrea Vaupel, Callum J Dickson, et al.Journal of Medicinal Chemistry|November 18, 2022
JDQ443, a Structurally Novel, Pyrazole-Based, Covalent Inhibitor of KRASG12C for the Treatment of Solid TumorsEdwige Lorthiois, Marc Gerspacher, Kim S Beyer, et al.Blood Cancer Journal|July 19, 2022
BRD9 degraders as chemosensitizers in acute leukemia and multiple myelomaEllen Weisberg, Basudev Chowdhury, Chengcheng Meng, et al.Cancer Discovery|April 11, 2022
Discovery, Preclinical Characterization, and Early Clinical Activity of JDQ443, a Structurally Novel, Potent, and Selective Covalent Oral Inhibitor of KRASG12CAndreas Weiss, Edwige Lorthiois, Louise Barys, et al.Nature Chemical Biology|January 19, 2021
BET bromodomain inhibitors regulate keratinocyte plasticityGabi Schutzius, Christian Kolter, Sebastian Bergling, et al.Pageof 2