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Drug Metabolism and Disposition: the Biological Fate of Chemicals|September 25, 2021
HLM-beads: Rapid Assessment of Nonspecific Binding to Human Liver Microsomes Using Magnetizable BeadsTing Wang, Andrea Whitcher-Johnstone, Monica Keith-Luzzi, et al.Clinical Pharmacology and Therapeutics|July 14, 2025
Advancing Predictions of Oral Drug Absorption, CYP3A4 Induction, and Transporter-Mediated Interactions Using a Human Primary Intestinal 3D Model (EpiIntestinal™)Paresh P Chothe, Andrea Whitcher-Johnstone, Aniruddha Karve, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|March 7, 2012
Metabolic switching of BILR 355 in the presence of ritonavir. II. Uncovering novel contributions by gut bacteria and aldehyde oxidaseYongmei Li, Jun Xu, W George Lai, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|June 19, 2014
A numerical method for analysis of in vitro time-dependent inhibition data. Part 2. Application to experimental dataKen Korzekwa, Donald Tweedie, Upendra A Argikar, et al.Clinical and Translational Science|March 19, 2024
Aminobenzotriazole inhibits and induces several key drug metabolizing enzymes complicating its utility as a pan CYP inhibitor for reaction phenotypingKrishna C Aluri, Marina Slavsky, Ying Tan, et al.Journal of Pharmaceutical Sciences|April 14, 2024
Comparison of Commonly Used and New Methods to Determine Small Molecule Non-Specific Binding to Human Liver MicrosomesTing Wang, Andrea Whitcher-Johnstone, Young Sun Scaringella, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|March 7, 2012
Metabolic switching of BILR 355 in the presence of ritonavir. I. Identifying an unexpected disproportionate human metaboliteYongmei Li, W George Lai, Andrea Whitcher-Johnstone, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|December 20, 2015
Contribution of Major Metabolites toward Complex Drug-Drug Interactions of Deleobuvir: In Vitro Predictions and In Vivo OutcomesRucha S Sane, Diane Ramsden, John P Sabo, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|November 18, 2021
Predictive In Vitro-In Vivo Extrapolation for Time Dependent Inhibition of CYP1A2, CYP2C8, CYP2C9, CYP2C19, and CYP2D6 Using Pooled Human Hepatocytes, Human Liver Microsomes, and a Simple Mechanistic Static ModelDiane Ramsden, Elke S Perloff, Andrea Whitcher-Johnstone, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|June 13, 2015
Defining the Role of Gut Bacteria in the Metabolism of Deleobuvir: In Vitro and In Vivo StudiesMichelle McCabe, Rucha S Sane, Monica Keith-Luzzi, et al.Pageof 2