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Nucleic Acids Research|May 1, 2013
Small molecule induced reactivation of mutant p53 in cancer cellsXiangrui Liu, Rainer Wilcken, Andreas C Joerger, et al.Proceedings of the National Academy of Sciences of the United States of America|July 25, 2008
Targeted rescue of a destabilized mutant of p53 by an in silico screened drugFrank M Boeckler, Andreas C Joerger, Gaurav Jaggi, et al.Journal of the American Chemical Society|March 24, 2012
Halogen-enriched fragment libraries as leads for drug rescue of mutant p53Rainer Wilcken, Xiangrui Liu, Markus O Zimmermann, et al.ACS Chemical Biology|September 18, 2015
Experimental and Theoretical Evaluation of the Ethynyl Moiety as a Halogen BioisostereRainer Wilcken, Markus O Zimmermann, Matthias R Bauer, et al.Cell Death & Disease|March 8, 2022
Evolutionary history of the p53 family DNA-binding domain: insights from an Alvinella pompejana homologQiang Zhang, Dimitrios-Ilias Balourdas, Bruno Baron, et al.Journal of Molecular Biology|April 5, 2011
Interaction of the p53 DNA-binding domain with its n-terminal extension modulates the stability of the p53 tetramerEviatar Natan, Cetin Baloglu, Kevin Pagel, et al.Future Medicinal Chemistry|June 5, 2014
Halogen-enriched fragment libraries as chemical probes for harnessing halogen bonding in fragment-based lead discoveryMarkus O Zimmermann, Andreas Lange, Rainer Wilcken, et al.Cell Death & Disease|February 26, 2026
Targeting the p53 cancer mutants Y220C, Y220N, and Y220S with the small-molecule stabilizer rezatapoptDanai Mavridi, Julianne S Funk, Dimitrios-Ilias Balourdas, et al.ACS Chemical Biology|January 29, 2020
Targeting Cavity-Creating p53 Cancer Mutations with Small-Molecule Stabilizers: the Y220X ParadigmMatthias R Bauer, Andreas Krämer, Giovanni Settanni, et al.ACS Chemical Biology|June 9, 2016
Harnessing Fluorine-Sulfur Contacts and Multipolar Interactions for the Design of p53 Mutant Y220C Rescue DrugsMatthias R Bauer, Rhiannon N Jones, Matthias G J Baud, et al.Pageof 8