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Journal of Medicinal Chemistry|June 4, 2021
Structure-Based Design of Selective Salt-Inducible Kinase InhibitorsRoberta Tesch, Marcel Rak, Monika Raab, et al.ACS Chemical Biology|January 31, 2024
Development of Potent Dual BET/HDAC Inhibitors via Pharmacophore Merging and Structure-Guided OptimizationNicolas Bauer, Dimitrios-Ilias Balourdas, Joel R Schneider, et al.Proceedings of the National Academy of Sciences of the United States of America|December 24, 2010
Electron microscopy studies on the quaternary structure of p53 reveal different binding modes for p53 tetramers in complex with DNARoberto Melero, Sridharan Rajagopalan, Melisa Lázaro, et al.European Journal of Medicinal Chemistry|February 8, 2019
New pyrido[3,4-g]quinazoline derivatives as CLK1 and DYRK1A inhibitors: synthesis, biological evaluation and binding mode analysisHelmi Tazarki, Wael Zeinyeh, Yannick J Esvan, et al.Cell Death and Differentiation|December 1, 2020
Identification and functional characterization of new missense SNPs in the coding region of the TP53 geneFlora Doffe, Vincent Carbonnier, Manon Tissier, et al.European Journal of Medicinal Chemistry|October 9, 2020
Selective targeting of the αC and DFG-out pocket in p38 MAPKSandra Röhm, Martin Schröder, Jessica E Dwyer, et al.International Journal of Molecular Sciences|April 3, 2021
Genotoxicity and Epigenotoxicity of Carbazole-Derived Molecules on MCF-7 Breast Cancer CellsClaudio Luparello, Ilenia Cruciata, Andreas C Joerger, et al.Journal of Medicinal Chemistry|December 21, 2023
Synthesis of Pyrazole-Based Macrocycles Leads to a Highly Selective Inhibitor for MST3Jennifer Alisa Amrhein, Lena Marie Berger, Dimitrios-Ilias Balourdas, et al.Proceedings of the National Academy of Sciences of the United States of America|April 28, 2026
DARPins as pan-reactivators of temperature-sensitive p53 cancer mutantsPhilipp Münick, Dimitrios-Ilias Balourdas, Julianne S Funk, et al.Nature Structural & Molecular Biology|January 9, 2025
DARPin-induced reactivation of p53 in HPV-positive cellsPhilipp Münick, Alexander Strubel, Dimitrios-Ilias Balourdas, et al.Pageof 8