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Andreas Heine

Showing results (21-30 of 134) with videos related to

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Journal of Molecular Biology|October 13, 2004
Analysis of the class I aldolase binding site architecture based on the crystal structure of 2-deoxyribose-5-phosphate aldolase at 0.99A resolutionAndreas Heine, John G Luz, Chi-Huey Wong, et al.
Chembiochem : a European Journal of Chemical Biology|October 3, 2003
Flexible adaptations in the structure of the tRNA-modifying enzyme tRNA-guanine transglycosylase and their implications for substrate selectivity, reaction mechanism and structure-based drug designRuth Brenk, Milton T Stubbs, Andreas Heine, et al.
Chemmedchem|December 7, 2019
Fragments as Novel Starting Points for tRNA-Guanine Transglycosylase Inhibitors Found by Alternative Screening StrategiesEngi Hassaan, Per-Olof Eriksson, Stefan Geschwindner, et al.
Archiv Der Pharmazie|April 17, 2024
What doesn't fit is made to fit: Pim-1 kinase adapts to the configuration of stilbene-based inhibitorsPhil M M Hochban, Lukas Heyder, Andreas Heine, et al.
Chemmedchem|June 6, 2023
Mutational Studies of Aldose Reductase to Trace a Transient Pocket Opening and to Explain Ligand Affinity CliffsLea-Sophie Klee, Marina Gárdonyi, Tobias Hüfner, et al.
Chemmedchem|October 8, 2020
Two Methods, One Goal: Structural Differences between Cocrystallization and Crystal Soaking to Discover Ligand Binding PosesBarbara Wienen-Schmidt, Matthias Oebbeke, Khang Ngo, et al.
Journal of the American Chemical Society|July 12, 2017
How Nothing Boosts Affinity: Hydrophobic Ligand Binding to the Virtually Vacated S<sub>1</sub>' Pocket of ThermolysinStefan G Krimmer, Jonathan Cramer, Johannes Schiebel, et al.
Journal of Molecular Biology|August 12, 2008
Structural and kinetic analysis of pyrrolidine-based inhibitors of the drug-resistant Ile84Val mutant of HIV-1 proteaseJark Böttcher, Andreas Blum, Andreas Heine, et al.
Chemmedchem|January 4, 2012
Experimental and computational active site mapping as a starting point to fragment-based lead discoveryJürgen Behnen, Helene Köster, Gerd Neudert, et al.
Biochimica Et Biophysica Acta|December 20, 2014
Thermodynamic signatures of fragment binding: Validation of direct versus displacement ITC titrationsEggert Rühmann, Michael Betz, Marie Fricke, et al.
Pageof 14

Showing results (21-30 of 134) with videos related to

Sort By:
Pageof 14
Journal of Molecular Biology|October 13, 2004
Analysis of the class I aldolase binding site architecture based on the crystal structure of 2-deoxyribose-5-phosphate aldolase at 0.99A resolutionAndreas Heine, John G Luz, Chi-Huey Wong, et al.
Chembiochem : a European Journal of Chemical Biology|October 3, 2003
Flexible adaptations in the structure of the tRNA-modifying enzyme tRNA-guanine transglycosylase and their implications for substrate selectivity, reaction mechanism and structure-based drug designRuth Brenk, Milton T Stubbs, Andreas Heine, et al.
Chemmedchem|December 7, 2019
Fragments as Novel Starting Points for tRNA-Guanine Transglycosylase Inhibitors Found by Alternative Screening StrategiesEngi Hassaan, Per-Olof Eriksson, Stefan Geschwindner, et al.
Archiv Der Pharmazie|April 17, 2024
What doesn't fit is made to fit: Pim-1 kinase adapts to the configuration of stilbene-based inhibitorsPhil M M Hochban, Lukas Heyder, Andreas Heine, et al.
Chemmedchem|June 6, 2023
Mutational Studies of Aldose Reductase to Trace a Transient Pocket Opening and to Explain Ligand Affinity CliffsLea-Sophie Klee, Marina Gárdonyi, Tobias Hüfner, et al.
Chemmedchem|October 8, 2020
Two Methods, One Goal: Structural Differences between Cocrystallization and Crystal Soaking to Discover Ligand Binding PosesBarbara Wienen-Schmidt, Matthias Oebbeke, Khang Ngo, et al.
Journal of the American Chemical Society|July 12, 2017
How Nothing Boosts Affinity: Hydrophobic Ligand Binding to the Virtually Vacated S<sub>1</sub>' Pocket of ThermolysinStefan G Krimmer, Jonathan Cramer, Johannes Schiebel, et al.
Journal of Molecular Biology|August 12, 2008
Structural and kinetic analysis of pyrrolidine-based inhibitors of the drug-resistant Ile84Val mutant of HIV-1 proteaseJark Böttcher, Andreas Blum, Andreas Heine, et al.
Chemmedchem|January 4, 2012
Experimental and computational active site mapping as a starting point to fragment-based lead discoveryJürgen Behnen, Helene Köster, Gerd Neudert, et al.
Biochimica Et Biophysica Acta|December 20, 2014
Thermodynamic signatures of fragment binding: Validation of direct versus displacement ITC titrationsEggert Rühmann, Michael Betz, Marie Fricke, et al.
Pageof 14