Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Filters

Andreas Heine

Showing results (51-60 of 134) with videos related to

Pageof 14
Sort By:
ACS Chemical Biology|October 23, 2019
Surprising Non-Additivity of Methyl Groups in Drug-Kinase InteractionBarbara Wienen-Schmidt, Denis Schmidt, Hans-Dieter Gerber, et al.
The Journal of Steroid Biochemistry and Molecular Biology|March 6, 2019
Mutational and structural studies uncover crucial amino acids determining activity and stability of 17β-HSD14Mohammed J Badran, Nicole Bertoletti, Aline Keils, et al.
Journal of Molecular Biology|May 5, 2009
More than a simple lipophilic contact: a detailed thermodynamic analysis of nonbasic residues in the s1 pocket of thrombinBernhard Baum, Menshawy Mohamed, Mohamed Zayed, et al.
ACS Chemical Biology|February 7, 2020
Conformational Changes in Alkyl Chains Determine the Thermodynamic and Kinetic Binding Profiles of Carbonic Anhydrase InhibitorsSteffen Glöckner, Khang Ngo, Christoph P Sager, et al.
Chemmedchem|March 18, 2020
Structure-Based Design of FXIIIa-Blockers: Addressing a Transient Hydrophobic Pocket in the Active Site of FXIIIaMartin Stieler, Christian Büchold, Marisa Schmitt, et al.
Journal of Medicinal Chemistry|December 10, 2016
Rational Design of Thermodynamic and Kinetic Binding Profiles by Optimizing Surface Water Networks Coating Protein-Bound LigandsStefan G Krimmer, Jonathan Cramer, Michael Betz, et al.
Proceedings of the National Academy of Sciences of the United States of America|March 25, 2005
Structural origins of efficient proton abstraction from carbon by a catalytic antibodyErik W Debler, Shuichiro Ito, Florian P Seebeck, et al.
Journal of Medicinal Chemistry|June 25, 2014
Beyond affinity: enthalpy-entropy factorization unravels complexity of a flat structure-activity relationship for inhibition of a tRNA-modifying enzymeManuel Neeb, Michael Betz, Andreas Heine, et al.
Journal of Medicinal Chemistry|February 13, 2010
Enhancement of hydrophobic interactions and hydrogen bond strength by cooperativity: synthesis, modeling, and molecular dynamics simulations of a congeneric series of thrombin inhibitorsLaveena Muley, Bernhard Baum, Michael Smolinski, et al.
Bioorganic & Medicinal Chemistry|August 10, 2016
Occupying a flat subpocket in a tRNA-modifying enzyme with ordered or disordered side chains: Favorable or unfavorable for binding?Manuel Neeb, Christoph Hohn, Frederik Rainer Ehrmann, et al.
Pageof 14

Showing results (51-60 of 134) with videos related to

Sort By:
Pageof 14
ACS Chemical Biology|October 23, 2019
Surprising Non-Additivity of Methyl Groups in Drug-Kinase InteractionBarbara Wienen-Schmidt, Denis Schmidt, Hans-Dieter Gerber, et al.
The Journal of Steroid Biochemistry and Molecular Biology|March 6, 2019
Mutational and structural studies uncover crucial amino acids determining activity and stability of 17β-HSD14Mohammed J Badran, Nicole Bertoletti, Aline Keils, et al.
Journal of Molecular Biology|May 5, 2009
More than a simple lipophilic contact: a detailed thermodynamic analysis of nonbasic residues in the s1 pocket of thrombinBernhard Baum, Menshawy Mohamed, Mohamed Zayed, et al.
ACS Chemical Biology|February 7, 2020
Conformational Changes in Alkyl Chains Determine the Thermodynamic and Kinetic Binding Profiles of Carbonic Anhydrase InhibitorsSteffen Glöckner, Khang Ngo, Christoph P Sager, et al.
Chemmedchem|March 18, 2020
Structure-Based Design of FXIIIa-Blockers: Addressing a Transient Hydrophobic Pocket in the Active Site of FXIIIaMartin Stieler, Christian Büchold, Marisa Schmitt, et al.
Journal of Medicinal Chemistry|December 10, 2016
Rational Design of Thermodynamic and Kinetic Binding Profiles by Optimizing Surface Water Networks Coating Protein-Bound LigandsStefan G Krimmer, Jonathan Cramer, Michael Betz, et al.
Proceedings of the National Academy of Sciences of the United States of America|March 25, 2005
Structural origins of efficient proton abstraction from carbon by a catalytic antibodyErik W Debler, Shuichiro Ito, Florian P Seebeck, et al.
Journal of Medicinal Chemistry|June 25, 2014
Beyond affinity: enthalpy-entropy factorization unravels complexity of a flat structure-activity relationship for inhibition of a tRNA-modifying enzymeManuel Neeb, Michael Betz, Andreas Heine, et al.
Journal of Medicinal Chemistry|February 13, 2010
Enhancement of hydrophobic interactions and hydrogen bond strength by cooperativity: synthesis, modeling, and molecular dynamics simulations of a congeneric series of thrombin inhibitorsLaveena Muley, Bernhard Baum, Michael Smolinski, et al.
Bioorganic & Medicinal Chemistry|August 10, 2016
Occupying a flat subpocket in a tRNA-modifying enzyme with ordered or disordered side chains: Favorable or unfavorable for binding?Manuel Neeb, Christoph Hohn, Frederik Rainer Ehrmann, et al.
Pageof 14