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Frontiers in Endocrinology|March 8, 2021
Redox Epiphospholipidome in Programmed Cell Death Signaling: Catalytic Mechanisms and RegulationValerian E Kagan, Yulia Y Tyurina, Irina I Vlasova, et al.
Journal of the American Chemical Society|December 12, 2018
Empowerment of 15-Lipoxygenase Catalytic Competence in Selective Oxidation of Membrane ETE-PE to Ferroptotic Death Signals, HpETE-PETamil S Anthonymuthu, Elizabeth M Kenny, Indira Shrivastava, et al.
Angewandte Chemie (International Ed. in English)|January 17, 2024
Strikingly High Activity of 15-Lipoxygenase Towards Di-Polyunsaturated Arachidonoyl/Adrenoyl-Phosphatidylethanolamines Generates Peroxidation Signals of Ferroptotic Cell DeathSvetlana N Samovich, Karolina Mikulska-Ruminska, Haider H Dar, et al.
Nature Chemical Biology|November 15, 2016
Oxidized arachidonic and adrenic PEs navigate cells to ferroptosisValerian E Kagan, Gaowei Mao, Feng Qu, et al.
Nature Cell Biology|September 17, 2013
Cardiolipin externalization to the outer mitochondrial membrane acts as an elimination signal for mitophagy in neuronal cellsCharleen T Chu, Jing Ji, Ruben K Dagda, et al.
Nature Communications|October 13, 2011
A mitochondria-targeted inhibitor of cytochrome c peroxidase mitigates radiation-induced deathJeffrey Atkinson, Alexandr A Kapralov, Naveena Yanamala, et al.
Journal of Leukocyte Biology|May 10, 2019
Redox (phospho)lipidomics of signaling in inflammation and programmed cell deathYulia Y Tyurina, Claudette M St Croix, Simon C Watkins, et al.
Cell|October 21, 2017
PEBP1 Wardens Ferroptosis by Enabling Lipoxygenase Generation of Lipid Death SignalsSally E Wenzel, Yulia Y Tyurina, Jinming Zhao, et al.
Redox Biology|February 1, 2022
Inactivation of RIP3 kinase sensitizes to 15LOX/PEBP1-mediated ferroptotic deathAndrew M Lamade, Limin Wu, Haider H Dar, et al.
Proceedings of the National Academy of Sciences of the United States of America|June 16, 2023
Discovering selective antiferroptotic inhibitors of the 15LOX/PEBP1 complex noninterfering with biosynthesis of lipid mediatorsHaider H Dar, Karolina Mikulska-Ruminska, Yulia Y Tyurina, et al.
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