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Andrew C Good

Showing results (21-30 of 34) with videos related to

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ACS Medicinal Chemistry Letters|June 20, 2020
Design and Synthesis of Styrenylcyclopropylamine LSD1 InhibitorsVictor S Gehling, John P McGrath, Martin Duplessis, et al.
Bioorganic & Medicinal Chemistry Letters|October 27, 2015
Macrocyclic prolinyl acyl guanidines as inhibitors of β-secretase (BACE)Kenneth M Boy, Jason M Guernon, Yong-Jin Wu, et al.
Bioorganic & Medicinal Chemistry Letters|July 26, 2011
Monosubstituted γ-lactam and conformationally constrained 1,3-diaminopropan-2-ol transition-state isostere inhibitors of β-secretase (BACE)Kenneth M Boy, Jason M Guernon, Jianliang Shi, et al.
Journal of Medicinal Chemistry|January 21, 2014
Hepatitis C virus NS5A replication complex inhibitors. Part 6: Discovery of a novel and highly potent biarylimidazole chemotype with inhibitory activity toward genotypes 1a and 1b repliconsMakonen Belema, Van N Nguyen, Jeffrey L Romine, et al.
Bioorganic & Medicinal Chemistry Letters|January 1, 2013
HCV NS5A replication complex inhibitors. Part 3: discovery of potent analogs with distinct core topologiesOmar D Lopez, Van N Nguyen, Denis R St Laurent, et al.
Journal of Medicinal Chemistry|October 4, 2012
Acyl guanidine inhibitors of β-secretase (BACE-1): optimization of a micromolar hit to a nanomolar lead via iterative solid- and solution-phase library synthesisSamuel W Gerritz, Weixu Zhai, Shuhao Shi, et al.
Journal of Medicinal Chemistry|October 15, 2016
Identification of (R)-N-((4-Methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-2-methyl-1-(1-(1-(2,2,2-trifluoroethyl)piperidin-4-yl)ethyl)-1H-indole-3-carboxamide (CPI-1205), a Potent and Selective Inhibitor of Histone Methyltransferase EZH2, Suitable for Phase I Clinical Trials for B-Cell LymphomasRishi G Vaswani, Victor S Gehling, Les A Dakin, et al.
ACS Medicinal Chemistry Letters|February 20, 2018
Potent Inhibitors of Hepatitis C Virus NS3 Protease: Employment of a Difluoromethyl Group as a Hydrogen-Bond DonorBarbara Zheng, Stanley V D'Andrea, Li-Qiang Sun, et al.
Journal of Medicinal Chemistry|November 24, 2025
Discovery of CFT8634, a Potent, Selective, and Orally Bioavailable Heterobifunctional Degrader of BRD9Katrina L Jackson, Ning Yin, Roman V Agafonov, et al.
Bioorganic & Medicinal Chemistry Letters|October 7, 2011
Synthesis and in vivo evaluation of cyclic diaminopropane BACE-1 inhibitorsLorin A Thompson, Jianliang Shi, Carl P Decicco, et al.
Pageof 4

Showing results (21-30 of 34) with videos related to

Sort By:
Pageof 4
ACS Medicinal Chemistry Letters|June 20, 2020
Design and Synthesis of Styrenylcyclopropylamine LSD1 InhibitorsVictor S Gehling, John P McGrath, Martin Duplessis, et al.
Bioorganic & Medicinal Chemistry Letters|October 27, 2015
Macrocyclic prolinyl acyl guanidines as inhibitors of β-secretase (BACE)Kenneth M Boy, Jason M Guernon, Yong-Jin Wu, et al.
Bioorganic & Medicinal Chemistry Letters|July 26, 2011
Monosubstituted γ-lactam and conformationally constrained 1,3-diaminopropan-2-ol transition-state isostere inhibitors of β-secretase (BACE)Kenneth M Boy, Jason M Guernon, Jianliang Shi, et al.
Journal of Medicinal Chemistry|January 21, 2014
Hepatitis C virus NS5A replication complex inhibitors. Part 6: Discovery of a novel and highly potent biarylimidazole chemotype with inhibitory activity toward genotypes 1a and 1b repliconsMakonen Belema, Van N Nguyen, Jeffrey L Romine, et al.
Bioorganic & Medicinal Chemistry Letters|January 1, 2013
HCV NS5A replication complex inhibitors. Part 3: discovery of potent analogs with distinct core topologiesOmar D Lopez, Van N Nguyen, Denis R St Laurent, et al.
Journal of Medicinal Chemistry|October 4, 2012
Acyl guanidine inhibitors of β-secretase (BACE-1): optimization of a micromolar hit to a nanomolar lead via iterative solid- and solution-phase library synthesisSamuel W Gerritz, Weixu Zhai, Shuhao Shi, et al.
Journal of Medicinal Chemistry|October 15, 2016
Identification of (R)-N-((4-Methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-2-methyl-1-(1-(1-(2,2,2-trifluoroethyl)piperidin-4-yl)ethyl)-1H-indole-3-carboxamide (CPI-1205), a Potent and Selective Inhibitor of Histone Methyltransferase EZH2, Suitable for Phase I Clinical Trials for B-Cell LymphomasRishi G Vaswani, Victor S Gehling, Les A Dakin, et al.
ACS Medicinal Chemistry Letters|February 20, 2018
Potent Inhibitors of Hepatitis C Virus NS3 Protease: Employment of a Difluoromethyl Group as a Hydrogen-Bond DonorBarbara Zheng, Stanley V D'Andrea, Li-Qiang Sun, et al.
Journal of Medicinal Chemistry|November 24, 2025
Discovery of CFT8634, a Potent, Selective, and Orally Bioavailable Heterobifunctional Degrader of BRD9Katrina L Jackson, Ning Yin, Roman V Agafonov, et al.
Bioorganic & Medicinal Chemistry Letters|October 7, 2011
Synthesis and in vivo evaluation of cyclic diaminopropane BACE-1 inhibitorsLorin A Thompson, Jianliang Shi, Carl P Decicco, et al.
Pageof 4