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Andrew D Hamilton

Showing results (161-170 of 180) with videos related to

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The Journal of Biological Chemistry|December 15, 2010
The BH3 alpha-helical mimic BH3-M6 disrupts Bcl-X(L), Bcl-2, and MCL-1 protein-protein interactions with Bax, Bak, Bad, or Bim and induces apoptosis in a Bax- and Bim-dependent mannerAslamuzzaman Kazi, Jiazhi Sun, Kenichiro Doi, et al.
Journal of Medicinal Chemistry|August 9, 2008
Potent, Plasmodium-selective farnesyltransferase inhibitors that arrest the growth of malaria parasites: structure-activity relationships of ethylenediamine-analogue scaffolds and homology model validationSteven Fletcher, Christopher G Cummings, Kasey Rivas, et al.
The Journal of Physical Chemistry. B|October 23, 2009
Design and evaluation of nonfluorous CO2-soluble oligomers and polymersYang Wang, Lei Hong, Deepak Tapriyal, et al.
Cancer Research|July 3, 2004
Akt/protein kinase B signaling inhibitor-2, a selective small molecule inhibitor of Akt signaling with antitumor activity in cancer cells overexpressing AktLin Yang, Han C Dan, Mei Sun, et al.
Cancer Research|May 20, 2004
Blocking angiogenesis and tumorigenesis with GFA-116, a synthetic molecule that inhibits binding of vascular endothelial growth factor to its receptorJiazhi Sun, Michelle A Blaskovich, Rishi K Jain, et al.
Blood|February 25, 2005
Farnesyltransferase inhibitor R115777 (Zarnestra, Tipifarnib) synergizes with paclitaxel to induce apoptosis and mitotic arrest and to inhibit tumor growth of multiple myeloma cellsKuichun Zhu, Elvira Gerbino, Darrin M Beaupre, et al.
Antimicrobial Agents and Chemotherapy|November 11, 2009
A novel class of meso-tetrakis-porphyrin derivatives exhibits potent activities against hepatitis C virus genotype 1b replicons in vitroYao Cheng, Lun K Tsou, Jianfeng Cai, et al.
Chemistry & Biology|February 28, 2009
Structural basis for binding and selectivity of antimalarial and anticancer ethylenediamine inhibitors to protein farnesyltransferaseMichael A Hast, Steven Fletcher, Christopher G Cummings, et al.
Organic & Biomolecular Chemistry|February 1, 2006
Structure-based design of imidazole-containing peptidomimetic inhibitors of protein farnesyltransferaseJunko Ohkanda, Corey L Strickland, Michelle A Blaskovich, et al.
Journal of Medicinal Chemistry|May 26, 2009
Structurally simple inhibitors of lanosterol 14alpha-demethylase are efficacious in a rodent model of acute Chagas diseasePraveen Kumar Suryadevara, Srinivas Olepu, Jeffrey W Lockman, et al.
Pageof 18

Showing results (161-170 of 180) with videos related to

Sort By:
Pageof 18
The Journal of Biological Chemistry|December 15, 2010
The BH3 alpha-helical mimic BH3-M6 disrupts Bcl-X(L), Bcl-2, and MCL-1 protein-protein interactions with Bax, Bak, Bad, or Bim and induces apoptosis in a Bax- and Bim-dependent mannerAslamuzzaman Kazi, Jiazhi Sun, Kenichiro Doi, et al.
Journal of Medicinal Chemistry|August 9, 2008
Potent, Plasmodium-selective farnesyltransferase inhibitors that arrest the growth of malaria parasites: structure-activity relationships of ethylenediamine-analogue scaffolds and homology model validationSteven Fletcher, Christopher G Cummings, Kasey Rivas, et al.
The Journal of Physical Chemistry. B|October 23, 2009
Design and evaluation of nonfluorous CO2-soluble oligomers and polymersYang Wang, Lei Hong, Deepak Tapriyal, et al.
Cancer Research|July 3, 2004
Akt/protein kinase B signaling inhibitor-2, a selective small molecule inhibitor of Akt signaling with antitumor activity in cancer cells overexpressing AktLin Yang, Han C Dan, Mei Sun, et al.
Cancer Research|May 20, 2004
Blocking angiogenesis and tumorigenesis with GFA-116, a synthetic molecule that inhibits binding of vascular endothelial growth factor to its receptorJiazhi Sun, Michelle A Blaskovich, Rishi K Jain, et al.
Blood|February 25, 2005
Farnesyltransferase inhibitor R115777 (Zarnestra, Tipifarnib) synergizes with paclitaxel to induce apoptosis and mitotic arrest and to inhibit tumor growth of multiple myeloma cellsKuichun Zhu, Elvira Gerbino, Darrin M Beaupre, et al.
Antimicrobial Agents and Chemotherapy|November 11, 2009
A novel class of meso-tetrakis-porphyrin derivatives exhibits potent activities against hepatitis C virus genotype 1b replicons in vitroYao Cheng, Lun K Tsou, Jianfeng Cai, et al.
Chemistry & Biology|February 28, 2009
Structural basis for binding and selectivity of antimalarial and anticancer ethylenediamine inhibitors to protein farnesyltransferaseMichael A Hast, Steven Fletcher, Christopher G Cummings, et al.
Organic & Biomolecular Chemistry|February 1, 2006
Structure-based design of imidazole-containing peptidomimetic inhibitors of protein farnesyltransferaseJunko Ohkanda, Corey L Strickland, Michelle A Blaskovich, et al.
Journal of Medicinal Chemistry|May 26, 2009
Structurally simple inhibitors of lanosterol 14alpha-demethylase are efficacious in a rodent model of acute Chagas diseasePraveen Kumar Suryadevara, Srinivas Olepu, Jeffrey W Lockman, et al.
Pageof 18