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Neurobiology of Disease|November 19, 2018
Reduction of microglial progranulin does not exacerbate pathology or behavioral deficits in neuronal progranulin-insufficient miceAndrew E Arrant, Anthony J Filiano, Aashka R Patel, et al.
Biorxiv : the Preprint Server for Biology|September 30, 2024
Carboxy-terminal blockade of sortilin binding enhances progranulin gene therapy, a potential treatment for frontotemporal dementiaShreya N Kashyap, Stephanie N Fox, Katherine I Wilson, et al.
Neurobiology of Disease|December 15, 2019
Behavioral defects associated with amygdala and cortical dysfunction in mice with seeded α-synuclein inclusionsLindsay E Stoyka, Andrew E Arrant, Drake R Thrasher, et al.
Plos One|December 9, 2014
Exposure to mitochondrial genotoxins and dopaminergic neurodegeneration in Caenorhabditis elegansClaudia P González-Hunt, Maxwell C K Leung, Rakesh K Bodhicharla, et al.
Annals of Clinical and Translational Neurology|November 16, 2020
Elevated levels of extracellular vesicles in progranulin-deficient mice and FTD-GRN PatientsAndrew E Arrant, Skylar E Davis, Rachael M Vollmer, et al.
Neurobiology of Disease|July 9, 2025
Reduction of sphingomyelinase activity associated with progranulin deficiency and frontotemporal dementiaNicholas R Boyle, Stephanie N Fox, Aniketh S Tadepalli, et al.
Acta Neuropathologica Communications|December 25, 2019
Impaired β-glucocerebrosidase activity and processing in frontotemporal dementia due to progranulin mutationsAndrew E Arrant, Jonathan R Roth, Nicholas R Boyle, et al.
Scientific Reports|July 19, 2025
TFEB overexpression alleviates autophagy-lysosomal deficits caused by progranulin insufficiencyWren O Nader, Kaylan S Brown, Nicholas R Boyle, et al.
The Journal of Experimental Medicine|August 27, 2014
Early retinal neurodegeneration and impaired Ran-mediated nuclear import of TDP-43 in progranulin-deficient FTLDMichael E Ward, Alice Taubes, Robert Chen, et al.
Acta Neuropathologica Communications|April 29, 2023
Patients with sporadic FTLD exhibit similar increases in lysosomal proteins and storage material as patients with FTD due to GRN mutationsSkylar E Davis, Anna K Cook, Justin A Hall, et al.
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