Showing results (1-10 of 67) with videos related to
Sort By:
Pageof 7
Journal of Pharmacological and Toxicological Methods|July 20, 2026
Predicting thorough QT safety profile using hERG IC10 versus IC50Andrew G Edwards, William J CrumbCurrent Protocols in Pharmacology|September 30, 2011
Patch-clamp studies of human cardiac ion channels in the evaluation of cardiac electrophysiological effects of compoundsWilliam J Crumb, Icilio CaveroJournal of Pharmacological and Toxicological Methods|December 24, 2018
Impact of disease state on arrhythmic event detection by action potential modelling in cardiac safety pharmacologyBernard Christophe, William J CrumbClinical and Translational Science|October 8, 2025
The Cardiac Sodium Channel Safety Profile of Cenobamate at Therapeutic Concentrations: In Vitro AnalysesWilliam J Crumb, Susan M Melnick, Kelli J GlennEuropean Journal of Pharmacology|September 27, 2003
Prulifloxacin: in vitro (HERG current) and in vivo (conscious dog) assessment of cardiac riskPierre Lacroix, William J Crumb, Lucia Durando, et al.Journal of Pharmacological and Toxicological Methods|April 10, 2016
An evaluation of 30 clinical drugs against the comprehensive in vitro proarrhythmia assay (CiPA) proposed ion channel panelWilliam J Crumb, Jose Vicente, Lars Johannesen, et al.Pharmacology Research & Perspectives|February 19, 2015
Oxytocin does not directly alter cardiac repolarization in rabbit or human cardiac myocytesYusheng Qu, Mei Fang, BaoXi Gao, et al.The Journal of Pharmacology and Experimental Therapeutics|April 19, 2002
Three-dimensional quantitative structure-activity relationship for inhibition of human ether-a-go-go-related gene potassium channelSean Ekins, William J Crumb, R Dustan Sarazan, et al.Clinical Medicine Insights. Cardiology|May 5, 2017
Species-Dependent Mechanisms of Cardiac Arrhythmia: A Cellular FocusAndrew G Edwards, William E LouchMolecular and Cellular Biochemistry|December 17, 2003
Characterization of the inhibitory effects of erythromycin and clarithromycin on the HERG potassium channelScott J C Stanat, Carol G Carlton, William J Crumb, et al.Pageof 7