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Human Molecular Genetics|June 1, 2022
Chromenone derivatives as novel pharmacological chaperones for retinitis pigmentosa-linked rod opsin mutantsJoseph T Ortega, Andrew G McKee, Francis J Roushar, et al.
Biophysical Journal|June 18, 2022
Towards generalizable predictions for G protein-coupled receptor variant expressionCharles P Kuntz, Hope Woods, Andrew G McKee, et al.
The Journal of Biological Chemistry|November 10, 2021
Systematic profiling of temperature- and retinal-sensitive rhodopsin variants by deep mutational scanningAndrew G McKee, Charles P Kuntz, Joseph T Ortega, et al.
Biorxiv : the Preprint Server for Biology|September 4, 2023
Divergent Folding-Mediated Epistasis Among Unstable Membrane Protein VariantsLaura M Chamness, Charles P Kuntz, Andrew G McKee, et al.
Elife|July 30, 2024
Divergent folding-mediated epistasis among unstable membrane protein variantsLaura M Chamness, Charles P Kuntz, Andrew G McKee, et al.
The Journal of Biological Chemistry|July 19, 2022
Molecular basis for variations in the sensitivity of pathogenic rhodopsin variants to 9-cis-retinalFrancis J Roushar, Andrew G McKee, Charles P Kuntz, et al.
Cell Chemical Biology|May 30, 2023
General trends in the effects of VX-661 and VX-445 on the plasma membrane expression of clinical CFTR variantsAndrew G McKee, Eli F McDonald, Wesley D Penn, et al.
Plos Biology|January 14, 2025
Discovery of non-retinoid compounds that suppress the pathogenic effects of misfolded rhodopsin in a mouse model of retinitis pigmentosaJoseph T Ortega, Jacklyn M Gallagher, Andrew G McKee, et al.
Science Advances|March 18, 2020
Probing biophysical sequence constraints within the transmembrane domains of rhodopsin by deep mutational scanningWesley D Penn, Andrew G McKee, Charles P Kuntz, et al.
Biorxiv : the Preprint Server for Biology|September 18, 2025
General Trends in the Calnexin-Dependent Expression and Pharmacological Rescue of Clinical CFTR VariantsAustin Tedman, John A Olson, Minsoo Kim, et al.
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