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The Journal of Clinical Investigation|February 19, 2026
Neuronal SEL1L-HRD1 ER-associated degradation is essential for motor function and survival in miceMauricio Torres, You Lu, Brent Pederson, et al.
Cell Metabolism|March 11, 2014
The ratio of macronutrients, not caloric intake, dictates cardiometabolic health, aging, and longevity in ad libitum-fed miceSamantha M Solon-Biet, Aisling C McMahon, J William O Ballard, et al.
Molecular Metabolism|November 18, 2017
Skeletal muscle overexpression of nicotinamide phosphoribosyl transferase in mice coupled with voluntary exercise augments exercise enduranceSheila R Costford, Bram Brouwers, Meghan E Hopf, et al.
The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences|June 27, 2026
The association of frailty with age and lifespan in mice differs by strain and sexDantong Zhu, Cara L Green, Sarah J Mitchell, et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|July 28, 2010
SIRT1 is essential for normal cognitive function and synaptic plasticityShaday Michán, Ying Li, Maggie Meng-Hsiu Chou, et al.
Cell|December 24, 2013
Declining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during agingAna P Gomes, Nathan L Price, Alvin J Y Ling, et al.
AIDS Research and Human Retroviruses|August 29, 2019
Harvard HIV and Aging Workshop: Perspectives and Priorities from Claude D. Pepper Centers and Centers for AIDS ResearchMonty Montano, Shalender Bhasin, Richard T D'Aquila, et al.
The Journal of Clinical Endocrinology and Metabolism|February 6, 2023
Nicotinamide Adenine Dinucleotide Augmentation in Overweight or Obese Middle-Aged and Older Adults: A Physiologic StudyKarol Mateusz Pencina, Rodrigo Valderrabano, Benjamin Wipper, et al.
Aging Cell|November 27, 2023
SIRT2 transgenic over-expression does not impact lifespan in miceLindsay E Wu, Corrine E Fiveash, Nicholas L Bentley, et al.
Cell Metabolism|October 13, 2016
NAD+ Replenishment Improves Lifespan and Healthspan in Ataxia Telangiectasia Models via Mitophagy and DNA RepairEvandro Fei Fang, Henok Kassahun, Deborah L Croteau, et al.
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