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Current Protocols in Chemical Biology|May 14, 2013
Target Identification by Diazirine Photo-Cross-linking and Click ChemistryAndrew L Mackinnon, Jack TauntonJournal of the American Chemical Society|November 7, 2007
Photo-leucine incorporation reveals the target of a cyclodepsipeptide inhibitor of cotranslational translocationAndrew L MacKinnon, Jennifer L Garrison, Ramanujan S Hegde, et al.Biochemistry|April 19, 2006
Half-of-sites binding of orotidine 5'-phosphate and alpha-D-5-phosphorylribose 1-diphosphate to orotate phosphoribosyltransferase from Saccharomyces cerevisiae supports a novel variant of the Theorell-Chance mechanism with alternating site catalysisRonald W McClard, Edward A Holets, Andrew L MacKinnon, et al.Elife|February 6, 2014
An allosteric Sec61 inhibitor traps nascent transmembrane helices at the lateral gateAndrew L Mackinnon, Ville O Paavilainen, Ajay Sharma, et al.Chemistry & Biology|September 28, 2011
Secretory protein profiling reveals TNF-α inactivation by selective and promiscuous Sec61 modulatorsSarah V Maifeld, Andrew L MacKinnon, Jennifer L Garrison, et al.Journal of Medicinal Chemistry|February 14, 2017
Discovery of an Inhibitor of the Proteasome Subunit Rpn11Christian Perez, Jing Li, Francesco Parlati, et al.Molecular Cancer Therapeutics|December 28, 2020
The Glutaminase Inhibitor CB-839 (Telaglenastat) Enhances the Antimelanoma Activity of T-Cell-Mediated ImmunotherapiesSruthy Varghese, Snigdha Pramanik, Leila J Williams, et al.Journal for Immunotherapy of Cancer|December 20, 2017
Inhibition of arginase by CB-1158 blocks myeloid cell-mediated immune suppression in the tumor microenvironmentSusanne M Steggerda, Mark K Bennett, Jason Chen, et al.Nature Chemical Biology|March 1, 2017
Capzimin is a potent and specific inhibitor of proteasome isopeptidase Rpn11Jing Li, Tanya Yakushi, Francesco Parlati, et al.Molecular Cancer Therapeutics|February 14, 2014
Antitumor activity of the glutaminase inhibitor CB-839 in triple-negative breast cancerMatt I Gross, Susan D Demo, Jennifer B Dennison, et al.Pageof 1