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The Journal of Biological Chemistry|June 27, 2015
The Phosphatidylinositol (3,4,5)-Trisphosphate-dependent Rac Exchanger 1·Ras-related C3 Botulinum Toxin Substrate 1 (P-Rex1·Rac1) Complex Reveals the Basis of Rac1 Activation in Breast Cancer CellsChristina M Lucato, Michelle L Halls, Lisa M Ooms, et al.
The Journal of Biological Chemistry|September 14, 2019
Ligand-dependent spatiotemporal signaling profiles of the μ-opioid receptor are controlled by distinct protein-interaction networksSrgjan Civciristov, Cheng Huang, Bonan Liu, et al.
The Journal of Biological Chemistry|April 17, 2021
SAGA and SAGA-like SLIK transcriptional coactivators are structurally and biochemically equivalentKlaudia Adamus, Cyril Reboul, Jarrod Voss, et al.
Nature Structural & Molecular Biology|December 10, 2021
The cryo-EM structure of the human neurofibromin dimer reveals the molecular basis for neurofibromatosis type 1Christopher J Lupton, Charles Bayly-Jones, Laura D'Andrea, et al.
Science Signaling|October 11, 2018
Preassembled GPCR signaling complexes mediate distinct cellular responses to ultralow ligand concentrationsSrgjan Civciristov, Andrew M Ellisdon, Ryan Suderman, et al.
Cells|January 16, 2020
Parsing the IL-37-Mediated Suppression of Inflammasome FunctionIna Rudloff, Holly K Ung, Jennifer K Dowling, et al.
Science Advances|November 20, 2024
Structure of the human TSC:WIPI3 lysosomal recruitment complexCharles Bayly-Jones, Christopher J Lupton, Laura D'Andrea, et al.
Science Signaling|August 19, 2025
Hox-C12 coordinates β<sub>2</sub>-adrenoceptor coupling to a cAMP/calcium feedforward loop to drive invasion in triple-negative breast cancerTerrance Lam, Bailey Cardwell, Bonan Liu, et al.
International Journal of Molecular Sciences|February 13, 2026
Characteristics of T-Cells Expressing IL-37 and Its Receptors in Inflammatory Bowel DiseaseIndiana Zorkau, Peter J Eggenhuizen, Marie Lee, et al.
Nature Structural & Molecular Biology|July 21, 2022
Structure of the metastatic factor P-Rex1 reveals a two-layered autoinhibitory mechanismYong-Gang Chang, Christopher J Lupton, Charles Bayly-Jones, et al.
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