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Journal of Medicinal Chemistry
|
December 23, 2008
Synthesis, reduction potentials, and antitubercular activity of ring A/B analogues of the bioreductive drug (6S)-2-nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine (PA-824)
Andrew M Thompson, Adrian Blaser, Robert F Anderson, et al.
ACS Medicinal Chemistry Letters
|
December 21, 2017
Antitubercular Nitroimidazoles Revisited: Synthesis and Activity of the Authentic 3-Nitro Isomer of Pretomanid
Andrew M Thompson, Muriel Bonnet, Ho H Lee, et al.
Journal of Medicinal Chemistry
|
November 13, 2010
Synthesis and structure-activity relationships of aza- and diazabiphenyl analogues of the antitubercular drug (6S)-2-nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine (PA-824)
Iveta Kmentova, Hamish S Sutherland, Brian D Palmer, et al.
Journal of Medicinal Chemistry
|
March 18, 2015
Synthesis and structure-activity relationships for extended side chain analogues of the antitubercular drug (6S)-2-nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine (PA-824)
Brian D Palmer, Hamish S Sutherland, Adrian Blaser, et al.
Organic Process Research & Development
|
May 26, 2017
Development of a Scalable Process for the Synthesis of DNDI-VL-2098: A Potential Preclinical Drug Candidate for the Treatment of Visceral Leishmaniasis
Vijay S Satam, Srinivasa Rao Pedada, Pasumpon Kamaraj, et al.
Journal of Medicinal Chemistry
|
August 18, 2011
Synthesis and structure-activity relationships of varied ether linker analogues of the antitubercular drug (6S)-2-nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5h-imidazo[2,1-b][1,3]oxazine (PA-824)
Andrew M Thompson, Hamish S Sutherland, Brian D Palmer, et al.
Journal of Medicinal Chemistry
|
December 14, 2011
Structure-activity relationships for amide-, carbamate-, and urea-linked analogues of the tuberculosis drug (6S)-2-nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine (PA-824)
Adrian Blaser, Brian D Palmer, Hamish S Sutherland, et al.
Journal of Medicinal Chemistry
|
November 26, 2009
Synthesis and structure-activity studies of biphenyl analogues of the tuberculosis drug (6S)-2-nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine (PA-824)
Brian D Palmer, Andrew M Thompson, Hamish S Sutherland, et al.
Journal of Medicinal Chemistry
|
December 9, 2009
Synthesis and structure-activity relationships of antitubercular 2-nitroimidazooxazines bearing heterocyclic side chains
Hamish S Sutherland, Adrian Blaser, Iveta Kmentova, et al.
Journal of Medicinal Chemistry
|
July 8, 2005
Synthesis and structure-activity relationships of soluble 7-substituted 3-(3,5-dimethoxyphenyl)-1,6-naphthyridin-2-amines and related ureas as dual inhibitors of the fibroblast growth factor receptor-1 and vascular endothelial growth factor receptor-2 tyrosine kinases
Andrew M Thompson, Amy M Delaney, James M Hamby, et al.
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of 4
Search research articles
Search
Showing results (11-20 of 37) with videos related to
Sort By:
Page
of 4
Journal of Medicinal Chemistry
|
December 23, 2008
Synthesis, reduction potentials, and antitubercular activity of ring A/B analogues of the bioreductive drug (6S)-2-nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine (PA-824)
Andrew M Thompson, Adrian Blaser, Robert F Anderson, et al.
ACS Medicinal Chemistry Letters
|
December 21, 2017
Antitubercular Nitroimidazoles Revisited: Synthesis and Activity of the Authentic 3-Nitro Isomer of Pretomanid
Andrew M Thompson, Muriel Bonnet, Ho H Lee, et al.
Journal of Medicinal Chemistry
|
November 13, 2010
Synthesis and structure-activity relationships of aza- and diazabiphenyl analogues of the antitubercular drug (6S)-2-nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine (PA-824)
Iveta Kmentova, Hamish S Sutherland, Brian D Palmer, et al.
Journal of Medicinal Chemistry
|
March 18, 2015
Synthesis and structure-activity relationships for extended side chain analogues of the antitubercular drug (6S)-2-nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine (PA-824)
Brian D Palmer, Hamish S Sutherland, Adrian Blaser, et al.
Organic Process Research & Development
|
May 26, 2017
Development of a Scalable Process for the Synthesis of DNDI-VL-2098: A Potential Preclinical Drug Candidate for the Treatment of Visceral Leishmaniasis
Vijay S Satam, Srinivasa Rao Pedada, Pasumpon Kamaraj, et al.
Journal of Medicinal Chemistry
|
August 18, 2011
Synthesis and structure-activity relationships of varied ether linker analogues of the antitubercular drug (6S)-2-nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5h-imidazo[2,1-b][1,3]oxazine (PA-824)
Andrew M Thompson, Hamish S Sutherland, Brian D Palmer, et al.
Journal of Medicinal Chemistry
|
December 14, 2011
Structure-activity relationships for amide-, carbamate-, and urea-linked analogues of the tuberculosis drug (6S)-2-nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine (PA-824)
Adrian Blaser, Brian D Palmer, Hamish S Sutherland, et al.
Journal of Medicinal Chemistry
|
November 26, 2009
Synthesis and structure-activity studies of biphenyl analogues of the tuberculosis drug (6S)-2-nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine (PA-824)
Brian D Palmer, Andrew M Thompson, Hamish S Sutherland, et al.
Journal of Medicinal Chemistry
|
December 9, 2009
Synthesis and structure-activity relationships of antitubercular 2-nitroimidazooxazines bearing heterocyclic side chains
Hamish S Sutherland, Adrian Blaser, Iveta Kmentova, et al.
Journal of Medicinal Chemistry
|
July 8, 2005
Synthesis and structure-activity relationships of soluble 7-substituted 3-(3,5-dimethoxyphenyl)-1,6-naphthyridin-2-amines and related ureas as dual inhibitors of the fibroblast growth factor receptor-1 and vascular endothelial growth factor receptor-2 tyrosine kinases
Andrew M Thompson, Amy M Delaney, James M Hamby, et al.
Page
of 4