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Cancer Research Communications|August 26, 2025
TGFβ Inhibition during Radiotherapy Enhances Immune Cell Infiltration and Decreases Metastases in Ewing SarcomaJessica D Daley, Elina Mukherjee, David Ferraro, et al.Proceedings of the National Academy of Sciences of the United States of America|August 17, 2023
CD44 acts as a coreceptor for cell-specific enhancement of signaling and regulatory T cell induction by TGM1, a parasite TGF-β mimicMaarten van Dinther, Kyle T Cunningham, Shashi Prakash Singh, et al.Biorxiv : the Preprint Server for Biology|November 28, 2023
The helminth TGF-β mimic TGM4 is a modular ligand that binds CD44, CD49d and TGF-β receptors to preferentially target myeloid cellsShashi P Singh, Danielle J Smyth, Kyle Cunningham, et al.The Journal of Biological Chemistry|February 24, 2017
An engineered transforming growth factor β (TGF-β) monomer that functions as a dominant negative to block TGF-β signalingSun Kyung Kim, Lindsey Barron, Cynthia S Hinck, et al.Journal of Extracellular Vesicles|December 20, 2022
TGFβ+ small extracellular vesicles from head and neck squamous cell carcinoma cells reprogram macrophages towards a pro-angiogenic phenotypeNils Ludwig, Saigopalakrishna S Yerneni, Juliana H Azambuja, et al.EMBO Reports|November 28, 2024
The TGF-β mimic TGM4 achieves cell specificity through combinatorial surface co-receptor bindingShashi P Singh, Danielle J Smyth, Kyle T Cunningham, et al.Science Advances|December 15, 2021
TGFBR3L is an inhibin B co-receptor that regulates female fertilityEmilie Brûlé, Ying Wang, Yining Li, et al.Nature Communications|November 25, 2017
A structurally distinct TGF-β mimic from an intestinal helminth parasite potently induces regulatory T cellsChris J C Johnston, Danielle J Smyth, Ravindra B Kodali, et al.Biorxiv : the Preprint Server for Biology|May 15, 2024
Design of High Affinity Binders to Convex Protein Target SitesWei Yang, Derrick R Hicks, Agnidipta Ghosh, et al.Nature Communications|February 26, 2025
Design of high-affinity binders to immune modulating receptors for cancer immunotherapyWei Yang, Derrick R Hicks, Agnidipta Ghosh, et al.Pageof 10