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Current Pharmaceutical Design
|
June 2, 2012
Using fragment-based technologies to target protein-protein interactions
Justin F Bower, Andrew Pannifer
Journal of the American Chemical Society
|
January 12, 2013
Structural insights into a unique inhibitor binding pocket in kinesin spindle protein
Venkatasubramanian Ulaganathan, Sandeep K Talapatra, Oliver Rath, et al.
Acta Crystallographica. Section D, Biological Crystallography
|
September 4, 2013
Analysis of the human cofilin 1 structure reveals conformational changes required for actin binding
Marta Klejnot, Mads Gabrielsen, Jenifer Cameron, et al.
SLAS Discovery : Advancing Life Sciences R & D
|
March 18, 2017
In Vitro Assay Development and HTS of Small-Molecule Human ABAD/17β-HSD10 Inhibitors as Therapeutics in Alzheimer's Disease
Laura Aitken, Gemma Baillie, Andrew Pannifer, et al.
Cell Communication and Signaling : CCS
|
October 8, 2014
A novel small-molecule MRCK inhibitor blocks cancer cell invasion
Mathieu Unbekandt, Daniel R Croft, Diane Crighton, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 20, 2011
Fragment based discovery of a novel and selective PI3 kinase inhibitor
Samantha J Hughes, David S Millan, Iain C Kilty, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 4, 2012
Design and synthesis of a novel pyrrolidinyl pyrido pyrimidinone derivative as a potent inhibitor of PI3Kα and mTOR
Phuong T Le, Hengmiao Cheng, Sacha Ninkovic, et al.
Chemmedchem
|
November 2, 2019
Synthesis and Structure-Activity Relationships of N-(4-Benzamidino)-Oxazolidinones: Potent and Selective Inhibitors of Kallikrein-Related Peptidase 6
Elena De Vita, Niels Smits, Helma van den Hurk, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 15, 2004
Imidazo[1,2-b]pyridazines: a potent and selective class of cyclin-dependent kinase inhibitors
Kate F Byth, Nicola Cooper, Janet D Culshaw, et al.
Bioorganic & Medicinal Chemistry Letters
|
February 19, 2019
Structure-based design, synthesis and biological evaluation of a novel series of isoquinolone and pyrazolo[4,3-c]pyridine inhibitors of fascin 1 as potential anti-metastatic agents
Stuart Francis, Daniel Croft, Alexander W Schüttelkopf, et al.
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of 2
Search research articles
Search
Showing results (1-10 of 11) with videos related to
Sort By:
Page
of 2
Current Pharmaceutical Design
|
June 2, 2012
Using fragment-based technologies to target protein-protein interactions
Justin F Bower, Andrew Pannifer
Journal of the American Chemical Society
|
January 12, 2013
Structural insights into a unique inhibitor binding pocket in kinesin spindle protein
Venkatasubramanian Ulaganathan, Sandeep K Talapatra, Oliver Rath, et al.
Acta Crystallographica. Section D, Biological Crystallography
|
September 4, 2013
Analysis of the human cofilin 1 structure reveals conformational changes required for actin binding
Marta Klejnot, Mads Gabrielsen, Jenifer Cameron, et al.
SLAS Discovery : Advancing Life Sciences R & D
|
March 18, 2017
In Vitro Assay Development and HTS of Small-Molecule Human ABAD/17β-HSD10 Inhibitors as Therapeutics in Alzheimer's Disease
Laura Aitken, Gemma Baillie, Andrew Pannifer, et al.
Cell Communication and Signaling : CCS
|
October 8, 2014
A novel small-molecule MRCK inhibitor blocks cancer cell invasion
Mathieu Unbekandt, Daniel R Croft, Diane Crighton, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 20, 2011
Fragment based discovery of a novel and selective PI3 kinase inhibitor
Samantha J Hughes, David S Millan, Iain C Kilty, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 4, 2012
Design and synthesis of a novel pyrrolidinyl pyrido pyrimidinone derivative as a potent inhibitor of PI3Kα and mTOR
Phuong T Le, Hengmiao Cheng, Sacha Ninkovic, et al.
Chemmedchem
|
November 2, 2019
Synthesis and Structure-Activity Relationships of N-(4-Benzamidino)-Oxazolidinones: Potent and Selective Inhibitors of Kallikrein-Related Peptidase 6
Elena De Vita, Niels Smits, Helma van den Hurk, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 15, 2004
Imidazo[1,2-b]pyridazines: a potent and selective class of cyclin-dependent kinase inhibitors
Kate F Byth, Nicola Cooper, Janet D Culshaw, et al.
Bioorganic & Medicinal Chemistry Letters
|
February 19, 2019
Structure-based design, synthesis and biological evaluation of a novel series of isoquinolone and pyrazolo[4,3-c]pyridine inhibitors of fascin 1 as potential anti-metastatic agents
Stuart Francis, Daniel Croft, Alexander W Schüttelkopf, et al.
Page
of 2