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Plos Genetics|July 16, 2026
A genomic-led strategy to anticipate drug safety effectsBrian R Ferolito, Andrea R V R Horimoto, Kai Gravel-Pucillo, et al.Nature Cardiovascular Research|February 6, 2025
Large-scale multi-omics identifies drug targets for heart failure with reduced and preserved ejection fractionDanielle Rasooly, Claudia Giambartolomei, Gina M Peloso, et al.RSC Medicinal Chemistry|December 2, 2024
Toward target 2035: EUbOPEN - a public-private partnership to enable & unlock biology in the openClaudia Tredup, Suzanne Ackloo, Hartmut Beck, et al.Nature Communications|July 10, 2023
Genome-wide association analysis and Mendelian randomization proteomics identify drug targets for heart failureDanielle Rasooly, Gina M Peloso, Alexandre C Pereira, et al.Nature Reviews. Drug Discovery|February 24, 2018
Unexplored therapeutic opportunities in the human genomeTudor I Oprea, Cristian G Bologa, Søren Brunak, et al.Nature Reviews. Drug Discovery|March 24, 2018
Unexplored therapeutic opportunities in the human genomeTudor I Oprea, Cristian G Bologa, Søren Brunak, et al.Nature Reviews. Chemistry|July 5, 2022
CACHE (Critical Assessment of Computational Hit-finding Experiments): A public-private partnership benchmarking initiative to enable the development of computational methods for hit-findingSuzanne Ackloo, Rima Al-Awar, Rommie E Amaro, et al.HGG Advances|December 11, 2025
Leveraging large-scale biobanks for therapeutic target discoveryBrian R Ferolito, Hesam Dashti, Claudia Giambartolomei, et al.Nature Medicine|April 10, 2021
Actionable druggable genome-wide Mendelian randomization identifies repurposing opportunities for COVID-19Liam Gaziano, Claudia Giambartolomei, Alexandre C Pereira, et al.RSC Medicinal Chemistry|February 25, 2022
Target 2035 - update on the quest for a probe for every proteinSusanne Müller, Suzanne Ackloo, Arij Al Chawaf, et al.Pageof 8