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Proceedings of the National Academy of Sciences of the United States of America|July 10, 2010
Global relevance of Aire binding to hypomethylated lysine-4 of histone-3Andrew S Koh, Robert E Kingston, Christophe Benoist, et al.Immunological Reviews|September 21, 2021
AIRE in context: Leveraging chromatin plasticity to trigger ectopic gene expressionCaroline Kaiser, Alexandra Bradu, Noah Gamble, et al.Cancer Immunology Research|May 29, 2024
Venetoclax Induces BCL-2-Dependent Treg to TH17 Plasticity to Enhance the Antitumor Efficacy of Anti-PD-1 Checkpoint BlockadeRosy Liao, Jocelyn Y Hsu, Nada S Aboelella, et al.Nature Immunology|January 17, 2018
Rapid chromatin repression by Aire provides precise control of immune toleranceAndrew S Koh, Erik L Miller, Jason D Buenrostro, et al.Nature|August 20, 2025
Thymic epithelial cells amplify epigenetic noise to promote immune toleranceNoah Gamble, Jason A Caldwell, Joshua McKeever, et al.Proceedings of the National Academy of Sciences of the United States of America|October 9, 2008
Aire employs a histone-binding module to mediate immunological tolerance, linking chromatin regulation with organ-specific autoimmunityAndrew S Koh, Alex J Kuo, Sang Youn Park, et al.Nature Immunology|April 17, 2024
PU.1 and BCL11B sequentially cooperate with RUNX1 to anchor mSWI/SNF to poise the T cell effector landscapeNoah Gamble, Alexandra Bradu, Jason A Caldwell, et al.Immunity|May 22, 2024
The CD8+ T cell tolerance checkpoint triggers a distinct differentiation state defined by protein translation defectsWillem Van Der Byl, Simone Nüssing, Timothy J Peters, et al.Pageof 1