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Journal of Pharmacokinetics and Pharmacodynamics|May 5, 2012
Implementation of dose superimposition to introduce multiple doses for a mathematical absorption model (transit compartment model)Jun Shen, Alison Boeckmann, Andrew Vick
The AAPS Journal|January 14, 2015
Using DTA and DTAARRAY variables and programming in WinNonlin ASCII models to streamline user-defined calculation and data analysisJun Shen, Shuanglian Li, Ronald R Bowsher, et al.
Drug Development and Industrial Pharmacy|January 13, 2016
Increased bioavailability of celecoxib under fed versus fasted conditions is determined by postprandial bile secretion as demonstrated in a dynamic gastrointestinal modelEric Lyng, Robert Havenaar, Prathap Shastri, et al.
Journal of Aerosol Medicine : the Official Journal of the International Society for Aerosols in Medicine|June 1, 2007
A 6-month inhalation study to characterize the toxicity, pharmacokinetics, and pharmacodynamics of human insulin inhalation powder (HIIP) in beagle dogsAndrew Vick, Ronald Wolff, Alan Koester, et al.
Journal of Clinical Pharmacology|April 23, 2014
A pharmacokinetic/pharmacodynamic model for AMG 416, a novel calcimimetic peptide, following a single intravenous dose in healthy subjectsJun Shen, Jim Xiao, Karen Pickthorn, et al.
Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association|November 16, 2013
Velcalcetide (AMG 416), a novel peptide agonist of the calcium-sensing receptor, reduces serum parathyroid hormone and FGF23 levels in healthy male subjectsKevin J Martin, Gregory Bell, Karen Pickthorn, et al.
Kidney International|August 2, 2013
AMG 416 (velcalcetide) is a novel peptide for the treatment of secondary hyperparathyroidism in a single-dose study in hemodialysis patientsKevin J Martin, Karen Pickthorn, Saling Huang, et al.
Molecular Metabolism|April 17, 2026
GIPR:GCGR co-agonism restores normal weight in obese rodentsDiego Perez-Tilve, Fa Zhang, Yujin Zhang, et al.
Molecular Therapy. Nucleic Acids|January 21, 2015
Predictive dose-based estimation of systemic exposure multiples in mouse and monkey relative to human for antisense oligonucleotides with 2'-o-(2-methoxyethyl) modificationsRosie Z Yu, John S Grundy, Scott P Henry, et al.
Phytotherapy Research : PTR|January 11, 2020
The effect of psyllium consumption on weight, body mass index, lipid profile, and glucose metabolism in diabetic patients: A systematic review and dose-response meta-analysis of randomized controlled trialsZhifang Xiao, Hui Chen, Yu Zhang, et al.
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