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Methods in Molecular Biology (Clifton, N.J.)|January 7, 2012
Chemical informatics: using molecular shape descriptors in structure-based drug designAndy JenningsJournal of Chemical Information and Modeling|September 11, 2007
Selection of molecules based on shape and electrostatic similarity: proof of concept of "electroforms"Andy Jennings, Mike TennantExpert Opinion on Drug Discovery|March 19, 2013
Discovery strategies in a pharmaceutical setting: the application of computational techniquesAndy Jennings, Mike TennantThe Journal of Biological Chemistry|October 30, 2004
Conformational flexibility in crystal structures of human 11beta-hydroxysteroid dehydrogenase type I provide insights into glucocorticoid interconversion and enzyme regulationDavid J Hosfield, Yiqin Wu, Robert J Skene, et al.Journal of Medicinal Chemistry|June 1, 2017
Repurposing Suzuki Coupling Reagents as a Directed Fragment Library Targeting Serine Hydrolases and Related EnzymesMarion Lanier, Derek C Cole, Yelena Istratiy, et al.Nature|July 22, 2014
High-resolution structure of the human GPR40 receptor bound to allosteric agonist TAK-875Ankita Srivastava, Jason Yano, Yoshihiko Hirozane, et al.Bioorganic & Medicinal Chemistry Letters|May 18, 2017
Discovery of potent and orally active 1,4-disubstituted indazoles as novel allosteric glucokinase activatorsZacharia S Cheruvallath, Stephen L Gwaltney, Mark Sabat, et al.Plos One|June 22, 2016
Trelagliptin (SYR-472, Zafatek), Novel Once-Weekly Treatment for Type 2 Diabetes, Inhibits Dipeptidyl Peptidase-4 (DPP-4) via a Non-Covalent MechanismCharles E Grimshaw, Andy Jennings, Ruhi Kamran, et al.Bioorganic & Medicinal Chemistry Letters|February 26, 2013
Design, synthesis and SAR of novel glucokinase activatorsZacharia S Cheruvallath, Stephen L Gwaltney, Mark Sabat, et al.The Journal of Biological Chemistry|April 6, 2005
Structural and kinetic analysis of the substrate specificity of human fibroblast activation protein alphaKathleen Aertgeerts, Irena Levin, Lihong Shi, et al.Pageof 2