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Bioorganic & Medicinal Chemistry Letters|July 16, 2013
Discovery of novel benzo[b][1,4]oxazin-3(4H)-ones as poly(ADP-ribose)polymerase inhibitorsAnthony R Gangloff, Jason Brown, Ron de Jong, et al.The Journal of Biological Chemistry|April 2, 2011
Structural analysis of the mechanism of inhibition and allosteric activation of the kinase domain of HER2 proteinKathleen Aertgeerts, Robert Skene, Jason Yano, et al.Journal of Medicinal Chemistry|December 29, 2010
Design and synthesis of pyrimidinone and pyrimidinedione inhibitors of dipeptidyl peptidase IVZhiyuan Zhang, Michael B Wallace, Jun Feng, et al.Bioorganic & Medicinal Chemistry Letters|July 23, 2019
Inhibition of 3-phosphoglycerate dehydrogenase (PHGDH) by indole amides abrogates de novo serine synthesis in cancer cellsEdouard Mullarky, Jiayi Xu, Anita D Robin, et al.Bioorganic & Medicinal Chemistry Letters|November 15, 2016
Discovery of TAK-659 an orally available investigational inhibitor of Spleen Tyrosine Kinase (SYK)Betty Lam, Yasuyoshi Arikawa, Joshua Cramlett, et al.Nature Chemical Biology|May 11, 2023
Signal peptide mimicry primes Sec61 for client-selective inhibitionShahid Rehan, Dale Tranter, Phillip P Sharp, et al.Proceedings of the National Academy of Sciences of the United States of America|February 2, 2026
Selective peroxynitrite-mediated protein nitration catalyzed by glyoxalase domain containing protein 4Sarah Wright, Vu C Dang, Sami Hussain, et al.Journal of Medicinal Chemistry|June 14, 2024
Design and Discovery of a Potent and Selective Inhibitor of Integrin αvβ1Mark Sabat, Daniel W Carney, Gloria Hernandez-Torres, et al.Pageof 2