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Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
June 17, 2021
Impact of Interindividual Differences in Plasma Fraction Unbound on the Pharmacokinetics of a Novel Syk Kinase Inhibitor in Beagle Dogs
Andy Pike, Barry Jones, Roshini Markandu, et al.
Journal of Pharmaceutical Sciences
|
November 28, 2020
A Novel Method for Preventing Non-specific Binding in Equilibrium Dialysis Assays Using Solutol® as an Additive
Abhishek Srivastava, Andy Pike, Beth Williamson, et al.
Journal of Medicinal Chemistry
|
April 24, 2025
In Vitro ADME Profiling of PROTACs: Successes, Challenges, and Lessons Learned from Analysis of Clinical PROTACs from a Diverse Physicochemical Space
Abhishek Srivastava, Andy Pike, Magda Swedrowska, et al.
Drug Discovery Today
|
July 22, 2020
Optimising proteolysis-targeting chimeras (PROTACs) for oral drug delivery: a drug metabolism and pharmacokinetics perspective
Andy Pike, Beth Williamson, Stephanie Harlfinger, et al.
Biopharmaceutics & Drug Disposition
|
September 4, 2018
The role of organic anion-transporting polypeptides and formulation in the clearance and distribution of a novel Na<sub>v</sub> 1.7 channel blocker
Andy Pike, Neil J Flanagan, R Ian Storer, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
April 29, 2024
The Role of Intramolecular Reactions and Chemical Degradation in the Apparent Biotransformation Pathways of a Series of SYK Inhibitors
Beatriz Calle, Bernard Barlaam, Coura Diène, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
February 4, 2006
Rat pharmacokinetics and pharmacodynamics of a sustained release formulation of the GABAA alpha5-selective compound L-655,708
John R Atack, Andy Pike, Ashley Clarke, et al.
Nature Reviews. Chemistry
|
December 13, 2025
Lessons learned in linking PROTACs from discovery to the clinic
Andy Pike, Esther C Y Lee, Iacovos N Michaelides, et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems
|
October 31, 2022
ADME and DMPK considerations for the discovery and development of antibody drug conjugates (ADCs)
Kevin Beaumont, Andy Pike, Michael Davies, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
April 11, 2023
Industry Perspective on the Pharmacokinetic and Absorption, Distribution, Metabolism, and Excretion Characterization of Heterobifunctional Protein Degraders
Laurie P Volak, Heide Marika Duevel, Sara Humphreys, et al.
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of 3
Search research articles
Search
Showing results (1-10 of 29) with videos related to
Sort By:
Page
of 3
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
June 17, 2021
Impact of Interindividual Differences in Plasma Fraction Unbound on the Pharmacokinetics of a Novel Syk Kinase Inhibitor in Beagle Dogs
Andy Pike, Barry Jones, Roshini Markandu, et al.
Journal of Pharmaceutical Sciences
|
November 28, 2020
A Novel Method for Preventing Non-specific Binding in Equilibrium Dialysis Assays Using Solutol® as an Additive
Abhishek Srivastava, Andy Pike, Beth Williamson, et al.
Journal of Medicinal Chemistry
|
April 24, 2025
In Vitro ADME Profiling of PROTACs: Successes, Challenges, and Lessons Learned from Analysis of Clinical PROTACs from a Diverse Physicochemical Space
Abhishek Srivastava, Andy Pike, Magda Swedrowska, et al.
Drug Discovery Today
|
July 22, 2020
Optimising proteolysis-targeting chimeras (PROTACs) for oral drug delivery: a drug metabolism and pharmacokinetics perspective
Andy Pike, Beth Williamson, Stephanie Harlfinger, et al.
Biopharmaceutics & Drug Disposition
|
September 4, 2018
The role of organic anion-transporting polypeptides and formulation in the clearance and distribution of a novel Na<sub>v</sub> 1.7 channel blocker
Andy Pike, Neil J Flanagan, R Ian Storer, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
April 29, 2024
The Role of Intramolecular Reactions and Chemical Degradation in the Apparent Biotransformation Pathways of a Series of SYK Inhibitors
Beatriz Calle, Bernard Barlaam, Coura Diène, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
February 4, 2006
Rat pharmacokinetics and pharmacodynamics of a sustained release formulation of the GABAA alpha5-selective compound L-655,708
John R Atack, Andy Pike, Ashley Clarke, et al.
Nature Reviews. Chemistry
|
December 13, 2025
Lessons learned in linking PROTACs from discovery to the clinic
Andy Pike, Esther C Y Lee, Iacovos N Michaelides, et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems
|
October 31, 2022
ADME and DMPK considerations for the discovery and development of antibody drug conjugates (ADCs)
Kevin Beaumont, Andy Pike, Michael Davies, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
April 11, 2023
Industry Perspective on the Pharmacokinetic and Absorption, Distribution, Metabolism, and Excretion Characterization of Heterobifunctional Protein Degraders
Laurie P Volak, Heide Marika Duevel, Sara Humphreys, et al.
Page
of 3