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Scientific Reports|October 13, 2022
Loss of stability and unfolding cooperativity in hPGK1 upon gradual structural perturbation of its N-terminal domain hydrophobic coreJuan Luis Pacheco-García, Dmitry S Loginov, Athi N Naganathan, et al.
Scientific Reports|March 15, 2017
Site-to-site interdomain communication may mediate different loss-of-function mechanisms in a cancer-associated NQO1 polymorphismEncarnación Medina-Carmona, Jose L Neira, Eduardo Salido, et al.
Journal of Neurochemistry|May 25, 2010
Effect of pharmacological chaperones on brain tyrosine hydroxylase and tryptophan hydroxylase 2Ana C Calvo, Tanja Scherer, Angel L Pey, et al.
Proteins|October 13, 2007
Engineering proteins with tunable thermodynamic and kinetic stabilitiesAngel L Pey, David Rodriguez-Larrea, Susanne Bomke, et al.
The FEBS Journal|November 15, 2022
Counterintuitive structural and functional effects due to naturally occurring mutations targeting the active site of the disease-associated NQO1 enzymeJuan Luis Pacheco-García, Ernesto Anoz-Carbonell, Dmitry S Loginov, et al.
ACS Omega|April 7, 2025
Engineered Oxalate Decarboxylase Boosts Activity and Stability for Biological ApplicationsMirco Dindo, Carolina Conter, Gen-Ichiro Uechi, et al.
FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology|August 29, 2006
Specific interaction of the diastereomers 7(R)- and 7(S)-tetrahydrobiopterin with phenylalanine hydroxylase: implications for understanding primapterinuria and vitiligoAngel L Pey, Aurora Martinez, Ramamurthy Charubala, et al.
Journal of Personalized Medicine|May 28, 2022
Targeting HIF-1α Function in Cancer through the Chaperone Action of NQO1: Implications of Genetic Diversity of NQO1Eduardo Salido, David J Timson, Isabel Betancor-Fernández, et al.
Protein Science : a Publication of the Protein Society|March 19, 2024
Structural dynamics and functional cooperativity of human NQO1 by ambient temperature serial crystallography and simulationsAlice Grieco, Sergio Boneta, José A Gavira, et al.
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