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International Journal of Biological Macromolecules|September 24, 2018
Phosphorylation compromises FAD binding and intracellular stability of wild-type and cancer-associated NQO1: Insights into flavo-proteome stabilityEncarnación Medina-Carmona, Bruno Rizzuti, Rubén Martín-Escolano, et al.
Plos One|March 12, 2011
The regulatory subunit of PKA-I remains partially structured and undergoes β-aggregation upon thermal denaturationKhanh K Dao, Angel L Pey, Anja Underhaug Gjerde, et al.
The Biochemical Journal|June 25, 2014
The consensus-based approach for gene/enzyme replacement therapies and crystallization strategies: the case of human alanine-glyoxylate aminotransferaseNoel Mesa-Torres, Cristina Yunta, Israel Fabelo-Rosa, et al.
FEBS Letters|September 19, 2023
Structural dynamics at the active site of the cancer-associated flavoenzyme NQO1 probed by chemical modification with PMSFAlice Grieco, Miguel A Ruiz-Fresneda, Atanasio Gómez-Mulas, et al.
Scientific Reports|February 4, 2016
Conformational dynamics is key to understanding loss-of-function of NQO1 cancer-associated polymorphisms and its correction by pharmacological ligandsEncarnación Medina-Carmona, Rogelio J Palomino-Morales, Julian E Fuchs, et al.
Archives of Biochemistry and Biophysics|September 12, 2022
Different phenotypic outcome due to site-specific phosphorylation in the cancer-associated NQO1 enzyme studied by phosphomimetic mutationsJuan Luis Pacheco-Garcia, Ernesto Anoz-Carbonell, Dmitry S Loginov, et al.
FEBS Letters|November 24, 2021
A single evolutionarily divergent mutation determines the different FAD-binding affinities of human and rat NQO1 due to site-specific phosphorylationJuan Luis Pacheco-Garcia, Dmitry Loginov, Bruno Rizzuti, et al.
FEBS Letters|January 20, 2024
Insights into the pathogenesis of primary hyperoxaluria type I from the structural dynamics of alanine:glyoxylate aminotransferase variantsPavla Vankova, Juan Luis Pacheco-Garcia, Dmitry S Loginov, et al.
Nucleic Acid Therapeutics|January 25, 2019
Systemic Alanine Glyoxylate Aminotransferase mRNA Improves Glyoxylate Metabolism in a Mouse Model of Primary Hyperoxaluria Type 1Anjli Kukreja, Melissa Lasaro, Christian Cobaugh, et al.
Human Mutation|October 2, 2004
Mechanisms underlying responsiveness to tetrahydrobiopterin in mild phenylketonuria mutationsAngel L Pey, Belén Pérez, Lourdes R Desviat, et al.
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