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Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
August 7, 2024
The Pharmacokinetics, Metabolism, and Clearance Mechanisms of Ritlecitinib, a Janus Kinase 3 and Tyrosine-Protein Kinase Family Inhibitor, in Humans
Jonathan N Bauman, Angela C Doran, Gabrielle M Gualtieri, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 25, 2008
3-(Imidazolyl methyl)-3-aza-bicyclo[3.1.0]hexan-6-yl)methyl ethers: a novel series of mGluR2 positive allosteric modulators
Lei Zhang, Bruce N Rogers, Allen J Duplantier, et al.
Biopharmaceutics & Drug Disposition
|
February 24, 2023
Investigating CNS distribution of PF-05212377, a P-glycoprotein substrate, by translation of 5-HT<sub>6</sub> receptor occupancy from non-human primates to humans
Aarti Sawant-Basak, Laigao Chen, Peter Lockwood, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
June 14, 2022
The Pharmacokinetics, Metabolism, and Clearance Mechanisms of Abrocitinib, a Selective Janus Kinase Inhibitor, in Humans
Jonathan N Bauman, Angela C Doran, Amanda King-Ahmad, et al.
ACS Chemical Neuroscience
|
June 14, 2017
Identification and Profiling of a Selective and Brain Penetrant Radioligand for in Vivo Target Occupancy Measurement of Casein Kinase 1 (CK1) Inhibitors
Travis T Wager, Paul Galatsis, Ramalakshmi Y Chandrasekaran, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
March 4, 2005
Use of a physiologically based pharmacokinetic model to study the time to reach brain equilibrium: an experimental analysis of the role of blood-brain barrier permeability, plasma protein binding, and brain tissue binding
Xingrong Liu, Bill J Smith, Cuiping Chen, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
June 9, 2006
Evaluation of cerebrospinal fluid concentration and plasma free concentration as a surrogate measurement for brain free concentration
Xingrong Liu, Bill J Smith, Cuiping Chen, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 31, 2009
3-Benzyl-1,3-oxazolidin-2-ones as mGluR2 positive allosteric modulators: Hit-to lead and lead optimization
Allen J Duplantier, Ivan Efremov, John Candler, et al.
Journal of Medicinal Chemistry
|
March 4, 2011
1-[(1-methyl-1H-imidazol-2-yl)methyl]-4-phenylpiperidines as mGluR2 positive allosteric modulators for the treatment of psychosis
Lei Zhang, Michael A Brodney, John Candler, et al.
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Search research articles
Search
Showing results (11-20 of 19) with videos related to
Sort By:
Page
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You have reached the last page of results.
This site can display upto 19 results.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
August 7, 2024
The Pharmacokinetics, Metabolism, and Clearance Mechanisms of Ritlecitinib, a Janus Kinase 3 and Tyrosine-Protein Kinase Family Inhibitor, in Humans
Jonathan N Bauman, Angela C Doran, Gabrielle M Gualtieri, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 25, 2008
3-(Imidazolyl methyl)-3-aza-bicyclo[3.1.0]hexan-6-yl)methyl ethers: a novel series of mGluR2 positive allosteric modulators
Lei Zhang, Bruce N Rogers, Allen J Duplantier, et al.
Biopharmaceutics & Drug Disposition
|
February 24, 2023
Investigating CNS distribution of PF-05212377, a P-glycoprotein substrate, by translation of 5-HT<sub>6</sub> receptor occupancy from non-human primates to humans
Aarti Sawant-Basak, Laigao Chen, Peter Lockwood, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
June 14, 2022
The Pharmacokinetics, Metabolism, and Clearance Mechanisms of Abrocitinib, a Selective Janus Kinase Inhibitor, in Humans
Jonathan N Bauman, Angela C Doran, Amanda King-Ahmad, et al.
ACS Chemical Neuroscience
|
June 14, 2017
Identification and Profiling of a Selective and Brain Penetrant Radioligand for in Vivo Target Occupancy Measurement of Casein Kinase 1 (CK1) Inhibitors
Travis T Wager, Paul Galatsis, Ramalakshmi Y Chandrasekaran, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
March 4, 2005
Use of a physiologically based pharmacokinetic model to study the time to reach brain equilibrium: an experimental analysis of the role of blood-brain barrier permeability, plasma protein binding, and brain tissue binding
Xingrong Liu, Bill J Smith, Cuiping Chen, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
June 9, 2006
Evaluation of cerebrospinal fluid concentration and plasma free concentration as a surrogate measurement for brain free concentration
Xingrong Liu, Bill J Smith, Cuiping Chen, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 31, 2009
3-Benzyl-1,3-oxazolidin-2-ones as mGluR2 positive allosteric modulators: Hit-to lead and lead optimization
Allen J Duplantier, Ivan Efremov, John Candler, et al.
Journal of Medicinal Chemistry
|
March 4, 2011
1-[(1-methyl-1H-imidazol-2-yl)methyl]-4-phenylpiperidines as mGluR2 positive allosteric modulators for the treatment of psychosis
Lei Zhang, Michael A Brodney, John Candler, et al.
Page
of 2