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Journal of Neuroimmunology|August 31, 2024
JAK inhibition in Down Syndrome Regression DisorderAngela L Rachubinski, Lina R Patel, Elise M Sannar, et al.Cell Reports|January 15, 2026
Altered hepatic metabolism in Down syndromeLauren N Dunn, Brian F Niemeyer, Neetha P Eduthan, et al.Biorxiv : the Preprint Server for Biology|June 12, 2025
Altered Hepatic Metabolism in Down SyndromeLauren N Dunn, Brian F Niemeyer, Neetha P Eduthan, et al.Annals of Clinical and Translational Neurology|February 25, 2025
Evidence of blood-brain barrier dysfunction and CSF immunoglobulin synthesis in Down Syndrome Regression DisorderJonathan D Santoro, Neetha Paul Eduthan, Mellad M Khoshnood, et al.Cell Death and Differentiation|January 21, 2023
Cell differentiation modifies the p53 transcriptional program through a combination of gene silencing and constitutive transactivationRoubina Tatavosian, Micah G Donovan, Matthew D Galbraith, et al.Nature Communications|June 28, 2024
Variegated overexpression of chromosome 21 genes reveals molecular and immune subtypes of Down syndromeMicah G Donovan, Neetha P Eduthan, Keith P Smith, et al.Cell Reports|December 28, 2022
IGF1 deficiency integrates stunted growth and neurodegeneration in Down syndromePaula Araya, Kohl T Kinning, Christina Coughlan, et al.Science Advances|June 28, 2023
Multidimensional definition of the interferonopathy of Down syndrome and its response to JAK inhibitionMatthew D Galbraith, Angela L Rachubinski, Keith P Smith, et al.Proceedings of the National Academy of Sciences of the United States of America|November 9, 2019
Trisomy 21 dysregulates T cell lineages toward an autoimmunity-prone state associated with interferon hyperactivityPaula Araya, Katherine A Waugh, Kelly D Sullivan, et al.Cell Reports|August 9, 2024
Multimodal analysis of dysregulated heme metabolism, hypoxic signaling, and stress erythropoiesis in Down syndromeMicah G Donovan, Angela L Rachubinski, Keith P Smith, et al.Pageof 3