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Angela M Lam

Showing results (21-30 of 37) with videos related to

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Viruses|March 28, 2024
Preclinical Antiviral and Safety Profiling of the HBV RNA Destabilizer AB-161Angela M Lam, Ravi R Dugyala, Muhammed Sheraz, et al.
Antiviral Research|May 24, 2011
Activity and the metabolic activation pathway of the potent and selective hepatitis C virus pronucleotide inhibitor PSI-353661Phillip A Furman, Eisuke Murakami, Congrong Niu, et al.
Bioorganic & Medicinal Chemistry Letters|August 16, 2012
β-D-2'-α-F-2'-β-C-Methyl-6-O-substituted 3',5'-cyclic phosphate nucleotide prodrugs as inhibitors of hepatitis C virus replication: a structure-activity relationship studyJinfa Du, Donghui Bao, Byoung-Kwon Chun, et al.
ACS Medicinal Chemistry Letters|September 18, 2024
Conformationally Constrained Isoquinolinones as Orally Efficacious Hepatitis B Capsid Assembly ModulatorsEugen F Mesaros, Andrew G Cole, Steven G Kultgen, et al.
ACS Infectious Diseases|September 22, 2024
Control of Hepatitis B Virus with Imdusiran, a Small Interfering RNA TherapeuticEmily P Thi, Xin Ye, Nicholas M Snead, et al.
Antimicrobial Agents and Chemotherapy|March 30, 2011
Inhibition of hepatitis C virus replicon RNA synthesis by PSI-352938, a cyclic phosphate prodrug of β-D-2'-deoxy-2'-α-fluoro-2'-β-C-methylguanosineAngela M Lam, Christine Espiritu, Eisuke Murakami, et al.
Journal of Medicinal Chemistry|November 8, 2024
Structure-Activity Relationships and Discovery of (<i>S</i>)-5-(<i>tert</i>-Butyl)-11-(difluoromethoxy)-9-methoxy-2-oxo-1,2,5,6-tetrahydropyrido[2',1':2,3]imidazo[4,5-<i>h</i>]quinoline-3-carboxylic Acid (AB-161), a Novel Orally Available and Liver-Centric HBV RNA DestabilizerDimitar Gotchev, Shuai Chen, Benjamin Dugan, et al.
Journal of Medicinal Chemistry|September 18, 2010
Discovery of a β-d-2'-deoxy-2'-α-fluoro-2'-β-C-methyluridine nucleotide prodrug (PSI-7977) for the treatment of hepatitis C virusMichael J Sofia, Donghui Bao, Wonsuk Chang, et al.
ACS Medicinal Chemistry Letters|June 6, 2014
Discovery of PSI-353661, a Novel Purine Nucleotide Prodrug for the Treatment of HCV InfectionWonsuk Chang, Donghui Bao, Byoung-Kwon Chun, et al.
Antimicrobial Agents and Chemotherapy|April 25, 2012
Metabolic activation of the anti-hepatitis C virus nucleotide prodrug PSI-352938Congrong Niu, Tatiana Tolstykh, Haiying Bao, et al.
Pageof 4

Showing results (21-30 of 37) with videos related to

Sort By:
Pageof 4
Viruses|March 28, 2024
Preclinical Antiviral and Safety Profiling of the HBV RNA Destabilizer AB-161Angela M Lam, Ravi R Dugyala, Muhammed Sheraz, et al.
Antiviral Research|May 24, 2011
Activity and the metabolic activation pathway of the potent and selective hepatitis C virus pronucleotide inhibitor PSI-353661Phillip A Furman, Eisuke Murakami, Congrong Niu, et al.
Bioorganic & Medicinal Chemistry Letters|August 16, 2012
β-D-2'-α-F-2'-β-C-Methyl-6-O-substituted 3',5'-cyclic phosphate nucleotide prodrugs as inhibitors of hepatitis C virus replication: a structure-activity relationship studyJinfa Du, Donghui Bao, Byoung-Kwon Chun, et al.
ACS Medicinal Chemistry Letters|September 18, 2024
Conformationally Constrained Isoquinolinones as Orally Efficacious Hepatitis B Capsid Assembly ModulatorsEugen F Mesaros, Andrew G Cole, Steven G Kultgen, et al.
ACS Infectious Diseases|September 22, 2024
Control of Hepatitis B Virus with Imdusiran, a Small Interfering RNA TherapeuticEmily P Thi, Xin Ye, Nicholas M Snead, et al.
Antimicrobial Agents and Chemotherapy|March 30, 2011
Inhibition of hepatitis C virus replicon RNA synthesis by PSI-352938, a cyclic phosphate prodrug of β-D-2'-deoxy-2'-α-fluoro-2'-β-C-methylguanosineAngela M Lam, Christine Espiritu, Eisuke Murakami, et al.
Journal of Medicinal Chemistry|November 8, 2024
Structure-Activity Relationships and Discovery of (<i>S</i>)-5-(<i>tert</i>-Butyl)-11-(difluoromethoxy)-9-methoxy-2-oxo-1,2,5,6-tetrahydropyrido[2',1':2,3]imidazo[4,5-<i>h</i>]quinoline-3-carboxylic Acid (AB-161), a Novel Orally Available and Liver-Centric HBV RNA DestabilizerDimitar Gotchev, Shuai Chen, Benjamin Dugan, et al.
Journal of Medicinal Chemistry|September 18, 2010
Discovery of a β-d-2'-deoxy-2'-α-fluoro-2'-β-C-methyluridine nucleotide prodrug (PSI-7977) for the treatment of hepatitis C virusMichael J Sofia, Donghui Bao, Wonsuk Chang, et al.
ACS Medicinal Chemistry Letters|June 6, 2014
Discovery of PSI-353661, a Novel Purine Nucleotide Prodrug for the Treatment of HCV InfectionWonsuk Chang, Donghui Bao, Byoung-Kwon Chun, et al.
Antimicrobial Agents and Chemotherapy|April 25, 2012
Metabolic activation of the anti-hepatitis C virus nucleotide prodrug PSI-352938Congrong Niu, Tatiana Tolstykh, Haiying Bao, et al.
Pageof 4