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Journal of Medicinal Chemistry|February 2, 2011
N-cyclic bay-substituted perylene G-quadruplex ligands have selective antiproliferative effects on cancer cells and induce telomere damageValentina Casagrande, Erica Salvati, Antonello Alvino, et al.Nucleic Acids Research|December 17, 2013
Evidence for G-quadruplex in the promoter of vegfr-2 and its targeting to inhibit tumor angiogenesisErica Salvati, Pasquale Zizza, Angela Rizzo, et al.The Journal of Clinical Investigation|October 13, 2007
Telomere damage induced by the G-quadruplex ligand RHPS4 has an antitumor effectErica Salvati, Carlo Leonetti, Angela Rizzo, et al.EMBO Molecular Medicine|November 25, 2022
MiR-182-3p targets TRF2 and impairs tumor growth of triple-negative breast cancerRoberto Dinami, Luca Pompili, Eleonora Petti, et al.Cellular & Molecular Biology Letters|October 20, 2025
Multi-omics analyses integration reveals a novel TRF2-miR-181a-5p-S100A10 regulatory axis in colon cancerRoberto Dinami, Eleonora Petti, Paola Ostano, et al.Nucleic Acids Research|December 8, 2016
SIRT6 interacts with TRF2 and promotes its degradation in response to DNA damageAngela Rizzo, Sara Iachettini, Erica Salvati, et al.Nucleic Acids Research|January 31, 2019
TRF2 positively regulates SULF2 expression increasing VEGF-A release and activity in tumor microenvironmentPasquale Zizza, Roberto Dinami, Manuela Porru, et al.Journal of Experimental & Clinical Cancer Research : CR|December 17, 2013
On and off-target effects of telomere uncapping G-quadruplex selective ligands based on pentacyclic acridinium saltsSara Iachettini, Malcolm Fg Stevens, Mark Frigerio, et al.Cell|July 27, 2010
TRF2 and apollo cooperate with topoisomerase 2alpha to protect human telomeres from replicative damageJing Ye, Christelle Lenain, Serge Bauwens, et al.Cell Death & Disease|March 30, 2025
TRF2 interaction with nuclear envelope is required for cell polarization and metastasis in triple negative breast cancerEleonora Petti, Serena Di Vito, Roberto Dinami, et al.Pageof 6