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Molecular Cell|March 17, 2009
SRC-induced disassembly of adherens junctions requires localized phosphorylation and degradation of the rac activator tiam1Simon A Woodcock, Claire Rooney, Michalis Liontos, et al.
Nature Cell Biology|October 12, 2010
SUMOylation of the GTPase Rac1 is required for optimal cell migrationSonia Castillo-Lluva, Michael H Tatham, Richard C Jones, et al.
Cancer|February 26, 2011
UHRF1-mediated tumor suppressor gene inactivation in nonsmall cell lung cancerAlexandros Daskalos, Urszula Oleksiewicz, Anastasia Filia, et al.
Nature Cell Biology|July 23, 2002
Tiam1 mediates Ras activation of Rac by a PI(3)K-independent mechanismJohn M Lambert, Que T Lambert, Gary W Reuther, et al.
Cell Reports|December 29, 2014
HUWE1 ubiquitylates and degrades the RAC activator TIAM1 promoting cell-cell adhesion disassembly, migration, and invasionLynsey Vaughan, Chong-Teik Tan, Anna Chapman, et al.
Cell Reports|November 10, 2021
TIAM1-RAC1 promote small-cell lung cancer cell survival through antagonizing Nur77-induced BCL2 conformational changeAishwarya Payapilly, Ryan Guilbert, Tine Descamps, et al.
Current Biology : CB|March 30, 2010
Tiam1-Rac signaling counteracts Eg5 during bipolar spindle assembly to facilitate chromosome congressionSimon A Woodcock, Helen J Rushton, Eduardo Castañeda-Saucedo, et al.
The Journal of Biological Chemistry|October 27, 2005
The rac activator Tiam1 is a Wnt-responsive gene that modifies intestinal tumor developmentAngeliki Malliri, Tomasz P Rygiel, Rob A van der Kammen, et al.
Nature Cell Biology|October 30, 2012
β2-syntrophin and Par-3 promote an apicobasal Rac activity gradient at cell-cell junctions by differentially regulating Tiam1 activityNatalie A Mack, Andrew P Porter, Helen J Whalley, et al.
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